Search results - 9 results
Identification of Flavouring Substances of Genotoxic Concern Present in E-Cigarette Refills
toxicity of e-cigarette vapours remains unclear. Considering the large number of e-liquid flavours available on the market (> 7000), there is an urgent need to establish an efficient screening strategy to ...
Chemometrics and chromatographic fingerprints to classify plant food supplements according to the content of regulated plants.
regulated or toxic plants is an important issue, especially when the products are purchased from irregular sources. This paper focusses on this problem by using specific chromatographic fingerprints for five ...
Detection of regulated herbs and plants in plant food supplements and traditional medicines using infrared spectroscopy.
identification of a specific toxic or regulated plant in herbal preparations or plant food supplements is a real challenge, since they are often powdered, mixed with other herbal or synthetic powders and ...
Development and validation of a HS/GC-MS method for the simultaneous analysis of diacetyl and acetylpropionyl in electronic cigarette refills
method methodology methods ON profile public public health Public-health Quality Quality Control Quantification SAFETY Sample Samples SCREENING study tobacco toxicity Toxicology use VALIDATION Abstract: ...
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
identification of experimental outliers, (2) overall assessment of robustness and inter-laboratory reproducibility and (3) re-classification of the unknown compounds to the respective toxicity classes. In summary, ...
Linking existing in vitro dermal absorption data to physicochemical properties: Contribution to the design of a weight-of-evidence approach for the safety evaluation of cosmetic ingredients with low dermal bioavailability.
No-Observed-Adverse-Effect Level Risk Assessment SKIN Skin Absorption Structure-Activity Relationship Toxicity Tests Abstract: To characterize the risk of cosmetic ingredients when threshold toxicity is assumed, often the ...
Headspace-gas chromatographic fingerprints to discriminate and classify counterfeit medicines.
guaranteed. Today, the safety evaluation of counterfeit medicines is mainly based on the identification and quantification of the active substances present. However, the analysis of potential toxic secondary ...
Development and validation of a fast chromatographic method for screening and quantification of legal and illegal skin whitening agents.
a number of illegal active substances including hydroquinone, tretinoin and corticosteroids. These may provoke as well local as systemic toxic effects, being the reason for their banning from the EU market. ...
Development and validation of a targeted LC-MS/MS quantitation method to monitor cell culture expression of tetanus neurotoxin during vaccine production
Issue HCT-17 (2022) Abstract: The tetanus neurotoxin (TeNT) is one of the most toxic proteins known to man, which prior to the use of the vaccine against the TeNT producing bacteria Clostridium tetani, ...