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Accuracy of HPV E6/E7 oncoprotein tests to detect high-grade cervical lesions: a systematic literature review and meta-analysis.

a pooled sensitivity of 46.9% (95% CI: 30.6-63.9) with a specificity of 98.0% (95% CI: 96.8-98.7). CONCLUSIONS: The high specificity of oncoprotein tests supports its use for triaging HPV-positive women. ...

Meta-analysis of the accuracy of p16 or p16/Ki-67 immunocytochemistry versus HPV testing for the detection of CIN2+/CIN3+ in triage of women with minor abnormal cytology.

Sensitivity and Specificity Severity of Illness Index triage Uterine Cervical Diseases Uterine Cervical Dysplasia Abstract: BACKGROUND: Women with atypical squamous cells of undetermined significance (ASC- US) ...

Prevention of Cervical Cancer: Guideline of the DGGG and the DKG (S3 Level, AWMF Register Number 015/027OL, December 2017)- Part 2 on Triage, Treatment and Follow-up.

this short summary deals with the triage, treatment and follow-up care of cervical dysplasia. With regard to those women who do not participate in screening, the guideline authors recommend sending out ...

Pathways to a cancer-free future: A protocol for modelled evaluations to maximize the future impact of interventions on cervical cancer in Australia

retaining vaccination uptake at the current level; vaccinating older women; increasing screening participation; methods for triaging HPV-positive women; improving the diagnosis of cervical intraepithelial ...

VALGENT: A protocol for clinical validation of human papillomavirus assays.

genotyping may be useful for triage in both HPV-based and cytology-based screening. Only clinically validated tests should be used in clinical practice. OBJECTIVES: VALGENT is a study framework for test ...

Cervical cancer screening program and Human Papillomavirus (HPV) testing, part II: Update on HPV primary screening.

and more. A two-step triage scenario with twice cytology at cutoff ASC- US + offers a good balance of efficiency (4 to 9 referrals to detect one CIN3 +, ~40% of referral) and safety (risk of CIN3 + in ...

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