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Host transcriptome profiling for resistance against lumpy skin disease (LSD).
Lumpy skin disease virus Male Pilot Projects Transcriptome Abstract: OBJECTIVE: Lumpy skin disease (LSD) is an acute or subacute systemic viral disease of cattle that shows variation in the response of ...
Physicochemical characterization and genotoxicity assessment of nanomaterials using new approach methodologies
containing a fraction of nanoparticles [4], as well as new innovative NAM s such as the transcriptomics-based biomarker, called GENOMARK. This NAM uses prediction models to classify analyzed materials as ...
Unraveling clonal CD8 T cell expansion and identification of essential factors in γ-herpesvirus-induced lymphomagenesis.
global phenotypic changes in circulating CD8 T cells after experimental infection of calves. T cell receptor repertoire together with transcriptomics and epigenomics analyses demonstrated an oligoclonal ...
Unlocking the Power of Transcriptomic Biomarkers in Qualitative and Quantitative Genotoxicity Assessment of Chemicals.
* Source: Chem Res Toxicol, Volume 37, Issue 3 (2024) Keywords: Animals Biomarkers Cell Line DNA Damage Gene Expression Profiling Humans Transcriptome Abstract: To modernize genotoxicity assessment and reduce ...
A Transcriptomic Biomarker to Classify Chemical-Induced Histone Deacetylase Inhibition in Human HepaRGTM Cells
Science Forum, Ottawa, Canada (2024) Keywords: HepaRG cells histone deacetylase inhibition transcriptomic biomarker Health Topics: Health and environment Santé et environnement Gezondheid en milieu ...
The GENOMARK transcriptomic biomarker: a new approach methodology for genotoxicity (Qualitative and quantitative aspects)
Source: Joint 3R Symposium 2023 (2023) Keywords: genotoxicity NAMs transcriptomic biomarker Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation des ...
Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals
Source: 57th Congress of the European Societies of Toxicology (Eurotox 2023), Ljubljana, Slovenia (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
Issue 2 (2023) Keywords: Algorithms Animals Biomarkers DNA Damage Gene Expression Profiling Humans Supervised Machine Learning Abstract: Transcriptomics-based biomarkers are promising new approach ...
The GENOMARK transcriptomic biomarker demonstrates a high predictivity for genotoxic hazards and utility in potency ranking in human HepaRGTM cells
Source: EEMGS meeting, Malaga, Spain (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health Topics: Health and environment Santé et environnement Gezondheid ...
The GENOMARK biomarker inhuman HepaRGTM cells: a new approach methodology for genotoxicity assessment
SaferWorldByDesign webinar, Online (2023) Keywords: genotoxicity NAM transcriptomic biomarker Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation des risques et de ...