Search results - 7 results

Genome Editing in Agriculture: Methods, Applications, and Governance—A paper in the series on The Need for Agricultural Innovation to Sustainably Feed the World by 2050

(CAST), Volume 60, Issue 60 (2018) Abstract: Genome editing is the process of making precise, targeted sequence changes in the deoxyribonucleic acid of living cells and organisms. Recent advances have made ...

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

for pharmaceutical, chemical, and consumer products, as afflicted compounds have to be (prematurely) abandoned or further tested on animals. Using the metabolically competent human HepaRG ™ cell line and toxicogenomics ...

Oxidative stress pathways involved in cytotoxicity and genotoxicity of titanium dioxide (TiO2) nanoparticles on cells constitutive of alveolo-capillary barrier in vitro.

Ghislaine Source: Toxicol In Vitro, Volume 33, Number 135, p.125-35 (2016) Keywords: Apoptosis Capillaries Cell Cycle Checkpoints Cell Line Cell Line, Tumor Cell Survival DNA Damage Glutathione Heat-Shock ...

Biosafety considerations for attenuated measles virus vectors used in virotherapy and vaccination.

cancer cells making them also attractive oncolytic vectors. The use of recombinant MV vector has to comply with various regulatory requirements, particularly relating to the assessment of potential risks ...

Biological activity conferred by endocrine disrupting chemicals in hospital effluent and river water from the Brussels Region, Belgium

gene expression) bioassay using a luciferase reporter gene as part of BG1 luc4E2 cells (human ovarian adenocarcinoma). Responses are time, dose, and ligand specific using 17β-estradiol (the natural ...

Systematic identification of hypothetical bacteriophage proteins targeting key protein complexes of pseudomonas aeruginosa

aeruginosa involved in transcription, DNA replication, fatty acid biosynthesis, RNA regulation, energy metabolism, and cell division during infection with members of seven distinct clades of lytic phages. ...

Development of giant bacteriophage phiKZ is independent of the host transcription apparatus

Journal of Virology, Volume 88, Issue 18, Number 10510, p.10501- 10510 (2014) Keywords: 0 Absence Activity article Bacterial Proteins Bacteriophages Belgium Beta Biology Cell data Development DNA-Directed ...

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