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Efficient control of Japanese encephalitis virus in the central nervous system of infected pigs occurs in the absence of a pronounced inflammatory immune response.

simultaneously observed, probably originating from infiltrating T cells, correlating with a fast suppression of JEV replication. The chemokine response was however not associated with the induction of a strong ...

Structural study of l-ascorbic acid 2-phosphate magnesium, a raw material in cell and tissue therapy

Publication Type: Peer reviewed scientific article Authors: Xu, X; Wozniczka, M; Van Hecke, K; Buyst, D; Mara, D; Vervaet, C; Herman, K; Wynendaele, Evelien; Deconinck, E.; De Spiegeleer, Bart Source: Journal of biological Inorganic Chemistry, Volume 25, ...

QuilA-Adjuvanted T. gondii Lysate Antigens Trigger Robust Antibody and IFNγ+ T Cell Responses in Pigs Leading to Reduction in Parasite DNA in Tissues Upon Challenge InfectionImage

results show that both the vaccine candidate and the TLA immunization elicited strong serum IgG responses and elevated percentages of CD4 + CD8 + IFN γ+ T cells in T. gondii infected pigs. However, the TLA ...

Phytochemical screening, antioxidant, anticoagulant and in vitro toxic and genotoxic properties of aerial parts extracts of Fumaria officinalis L. growing in Tunisia

tests. In vitro toxic and genotoxic properties with respectively the Neutral red uptake method and the bacterial Vitotox test and comet assay in human C3A cells. This study showed that methanolic extract ...

ADVANCE database characterisation and fit for purpose assessment for multi-country studies on the coverage, benefits and risks of pertussis vaccinations.

events (pertussis, pneumonia, death, fever, convulsions, injection site reactions, hypotonic hypo-responsive episode, persistent crying) and vaccines (acellular pertussis and whole cell pertussis) related ...

In Vitro and In Vivo Toxicity Studies on Cymbopogon giganteus Chiov. Leaves Essential Oil from Benin

administration of a single dose of 5% or 2% v/v. Single doses of 0.125% or 0.5% v/v did not induce inflammation, cell recruitment nor cytotoxicity in lungs 3 h or 24 h after administration, suggesting safety at ...

In vitro 50 Hz magnetic field long-term exposure: Cytogenetic tests on human lymphoblastoid TK6 cells and validation of the test environment

effects of long-term exposure to ELF-(E) MF s on the genetic material and the impact of long-term pre-exposure to ELF-(E) MF s on the sensitivity of cells to the damage induced by known mutagens are needed. ...

Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice

lung epithelial cells. Lung inflammation, acute phase response and genotoxicity were assessed 1, 3, and 28 days after a single intratracheal instillation of adult female C57BL /6 J BomTac mice. The doses ...

In vitro toxicity, genotoxicity and antigenotoxicity of Nigella sativa extracts from different geographic locations

micronucleus and comet tests in human C3A cells to investigate the in vitro cytotoxicity, genotoxicity and antigenotoxicity of aqueous seed extracts of this plant originating from three different regions ...

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