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In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.

Viral Drug Discovery Foot-and-Mouth Disease Models, Theoretical Oximes Ribavirin RNA, Viral Sulfonamides Virus Cultivation Virus Replication Abstract: Foot-and-mouth disease virus (FMDV) is a highly ...

Limited interlaboratory comparison of Schmallenberg virus antibody detection in serum samples.

Schirrmeier, H; Beer, M Source: Vet Rec, Volume 174, Issue 15, p.380 (2014) Keywords: Animals Antibodies, Viral Bunyaviridae Infections Cattle Cattle Diseases Enzyme-Linked Immunosorbent Assay Europe ...

Cytokine and immunoglobulin isotype profiles during CP7_E2alf vaccination against a challenge with the highly virulent Koslov strain of classical swine fever virus.

Vaccination Vaccines, Attenuated Viral Vaccines Abstract: CP7_E2alf is a promising marker vaccine candidate against classical swine fever (CSF). To better understand the mechanisms of protection, cytokine and ...

Sustained stimulation and expansion of Tregs by IL2 control autoimmunity without impairing immune responses to infection, vaccination and cancer.

by Tregs. We used recombinant adeno-associated viral vector (rAAV)-mediated gene transfer to continuously release IL2 in mice and assessed its long-term effects on immune responses. A single rAAV- IL2 ...

Bluetongue, Schmallenberg- what is next? Culicoides-borne viral diseases in the 21st Century.

Publication Type: Peer reviewed scientific article Authors: Koenraadt, Constantianus Jm; Balenghien, Thomas; Carpenter, Simon; Ducheyne, Els; Elbers, Armin Rw; Fife, Mark; Garros, Claire; Ibáñez-Justicia, Adolfo; Kampen, Helge; Kormelink, Richard Jm; Loss ...

Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.

Lefebvre, David; Lanke, Kjerstin H W; Kris De Clercq; Hilgenfeld, Rolf; Neyts, Johan; van Kuppeveld, Frank J M Source: Antiviral Res, Volume 103, p.17-24 (2014) Keywords: 3C Viral Proteases Animals Antiviral ...

Efficacy of marker vaccine candidate CP7_E2alf against challenge with classical swine fever virus isolates of different genotypes.

Microbiol, Volume 169, Issue 1-2, p.8-17 (2014) Keywords: Administration, Oral Animals Antibodies, Viral Classical Swine Fever Classical swine fever virus Genotype Injections, Intramuscular Sus scrofa Swine ...

Pulmonary artery haemorrhage in newborn calves following bluetongue virus serotype 8 experimental infections of pregnant heifers.

Claude Source: Vet Microbiol, Volume 167, Issue 3-4, p.250-9 (2013) Keywords: Animals Antibodies, Neutralizing Antibodies, Viral Bluetongue Bluetongue virus brain Cattle Cattle Diseases Europe Female milk ...

Development, validation and evaluation of added diagnostic value of a q(RT)-PCR for the detection of genotype A strains of small ruminant lentiviruses.

Goats Lentivirus Lentivirus Infections Molecular Diagnostic Techniques Molecular Sequence Data Real-Time Polymerase Chain Reaction RNA, Viral Sensitivity and Specificity Sequence Analysis, DNA Sheep Sheep ...

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