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The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.

(e.g., poliovirus, coxsackievirus, rhinovirus, and enterovirus 71) for which no antiviral drugs are available. The viral RNA-dependent RNA polymerase is an attractive target for antiviral therapy ...

Intra-host variation structure of classical swine fever virus NS5B in relation to antiviral therapy.

Substitution Animals Antiviral Agents Classical Swine Fever Classical swine fever virus Enzyme Inhibitors Genetic Variation Imidazoles Pyridines RNA Replicase Swine Viral Proteins Abstract: Classical swine fever ...

Isolation of Drug-Resistant Gallibacterium anatis from Calves with Unresponsive Bronchopneumonia, Belgium.

samples of 10 calves with bronchopneumonia unresponsive to antimicrobial therapy. Collected isolates were multidrug-resistant to extensively drug-resistant, exhibiting resistance against 5-7 classes of ...

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