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A systematic review and meta-analysis of host genetic factors associated with influenza severity

Publication Type: Peer reviewed scientific article Authors: Nina Van Goethem; Célestin Danwang; Nathalie Bossuyt; Herman Van Oyen; Nancy Roosens; Robert, Annie Source: BMC Genomics, Volume 22, Issue ...

A systematic review and meta-analysis of host genetic factors associated with influenza severity

Publication Type: Peer reviewed scientific article Authors: Nina Van Goethem; Célestin Danwang; Nathalie Bossuyt; Herman Van Oyen; Nancy Roosens; Robert, Annie Source: BMC Genomics, Volume 22, Issue ...

Attenuation of RNA viruses by redirecting their evolution in sequence space.

variability and, consequently, on their adaptive potential. We describe a strategy to attenuate RNA viruses by altering their evolutionary potential. We rationally altered the genomes of Coxsackie B3 and ...

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