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Comprehensive toxicokinetic analysis reveals major interspecies differences in absorption, distribution and elimination of citrinin in pigs and broiler chickens
L/kg after IV administration). However, plasma protein binding did not differ statistically significant (91-98%). It is imperative to further investigate biotransformation and elimination pathways in ...
Veal Calves Produce Less Antibodies against C. Perfringens Alpha Toxin Compared to Beef Calves.
Antibodies, Bacterial Bacterial Toxins Calcium-Binding Proteins Cattle Cattle Diseases Clostridium perfringens Enterotoxemia Immunity, Maternally-Acquired Type C Phospholipases Abstract: Enterotoxaemia is ...
Diversity of antimicrobial resistance and virulence genes in methicillin-resistant non-Staphylococcus aureus staphylococci from veal calves.
fibronectin-binding protein genes. MRNAS were highly multi-resistant and represent an important reservoir of antimicrobial resistance and virulence genes. Health Topics: Animal health Category: A1 FOS ...
The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.
template-primer duplex. Elucidation of a crystal structure of the inhibitor bound to CVB3 3Dpol confirmed the RNA-binding channel as the target for GPC- N114. Docking studies of the compound into the crystal ...
Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.
Agents Cell Line Cysteine Endopeptidases Drug Evaluation, Preclinical Genes, Reporter Humans Luciferases, Firefly Picornaviridae Protease Inhibitors Viral Proteins Abstract: Proteolytical cleavage of the ...
Antibacterial activity of a lectin-like Burkholderia cenocepacia protein.
previously been characterized in the γ-proteobacteria Pseudomonas and Xanthomonas. These proteins are composed of two MMBL (monocot mannose-binding lectin) domains, a module predominantly and abundantly found ...
M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.
Bert; Grooten, Johan; Fiers, Walter; Saelens, Xavier Source: PLoS One, Volume 8, Issue 3, p.e59081 (2013) Keywords: Adaptive Immunity Adaptor Proteins, Vesicular Transport Animals Female Humans Immunity, ...
Antibody evasion by a gammaherpesvirus O-glycan shield.
Sequence Alignment Viral Envelope Proteins Virion Virus Replication Abstract: All gammaherpesviruses encode a major glycoprotein homologous to the Epstein-Barr virus gp350. These glycoproteins are often ...
The bovine herpesvirus 4 Bo10 gene encodes a nonessential viral envelope protein that regulates viral tropism through both positive and negative effects.
attachment both by binding to cells and by covering another receptor-binding protein until they are displaced. Thus, they regulate viral tropism both positively and negatively depending upon the presence or ...
Identification of a dominant epitope in the hemagglutinin of an Asian highly pathogenic avian influenza H5N1 clade 1 virus by selection of escape mutants.
Molecular Mutation Neutralization Tests Viral Proteins Abstract: H5N1 avian influenza virus has caused widespread infection in poultry and wild birds, and has the potential to emerge as a pandemic threat to ...