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RNA-based drug susceptibility testing of Mycobacterium tuberculosis
pump overexpression, and (d) ignore the multifactorial influence of compensatory mutations. Here, we introduce a next-generation diagnostic test based on quantification of antibiotic-specific RNA ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
Publication Type: Scientific poster, presentation or proceeding Authors: An Van den Bossche; Roby Bhattacharyya; Jean-Yves Coppee; Leen Rigouts; Alain Baulard; Deborah Hung; Vanessa Mathys; Pieter-Jan Ceyssens Source: 39th Annual Congress of the European ...
The Phage-Encoded-Acetyltransferase Rac Mediates Inactivation of Transcription by Cleavage of the RNA Polymerase Alpha Subunit.
study, we describe the biological function of the phage-encoded protein RNA polymerase alpha subunit cleavage protein (Rac), a predicted Gcn5-related acetyltransferase encoded by phiKMV-like viruses. These ...
Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid.
to a pressure of the recently approved delamanid is investigated. Total RNA sequencing revealed that the response to this bicyclic nitroimidazole shows many similarities with pretomanid, an ...