Search results - 298 results

Shotgun metagenomics as a ONE Health tool for better protecting human health

taxonomic classification up to an unprecedented sensitivity, including the identification of linked specific genes, such as AMR or virulence genes. We are developing and optimizing the protocols (from DNA ...

Ultrastable Silver Nanoparticles for Rapid Serology Detection of Anti-SARS-CoV-2 Immunoglobulins G.

Sensitivity and Specificity Silver Spike Glycoprotein, Coronavirus Abstract: Dipstick assays using silver nanoparticles (AgNPs) stabilized by a thin calix [4]arene-based coating were developed and used for the ...

Clinical and analytical evaluation of the Alinity m HR HPV assay within the VALGENT-3 framework

Alinity m, RealTime, and cobas, and the Linear Array (Roche) was used for more detailed genotyping concordance. In the total study population, the relative sensitivity and specificity for CIN2 + and CIN3 ...

The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.

107/15,667 (0·7%) were deemed consistent with susceptibility. For rifampicin, isoniazid, ethambutol, fluoroquinolones, and streptomycin, the mutations’ pooled sensitivity was >80%. Specificity was over 95% ...

Development and validation of a microfluidic multiplex immunoassay for the determination of levels and avidity of serum antibodies to tetanus, diphtheria and pertussis antigens.

microfluidic channels of the assay cartridges of the system. The developed assay showed very good sensitivity, specificity, and intra- and inter-assay coefficients of variation (CV s for the different antigens ...

Importance of anti-SARS-CoV-2 assay antigenic composition as revealed by the results of the Belgian external quality assessment (EQA) scheme.

Immunoglobulin A Immunoglobulin G Immunoglobulin M Male Phosphoproteins SARS-CoV-2 Sensitivity and Specificity Spike Glycoprotein, Coronavirus Abstract: We report on sample IS /17575 since it generated highly ...

Measuring disability-adjusted life years (DALYs) due to COVID-19 in Scotland, 2020

certificates. We calculated DALY s based on the COVID-19 consensus model and methods outlined by the European Burden of Disease Network. DALY s were presented as a range, using a sensitivity analysis based on ...

Strategy and Performance Evaluation of Low-Frequency Variant Calling for SARS-CoV-2 Using Targeted Deep Illumina Sequencing

approach and Illumina sequencing. As anticipated, higher variation and lower sensitivity were observed at lower coverages and allelic frequencies. We found that detection of all low-frequency variants at an ...

Reliability of Morphological and PCR Methods for the Official Diagnosis of Aethina tumida (Coleoptera: Nitidulidae): A European Inter-Laboratory Comparison.

specificity. Sensitivity was satisfactory for all the participants and both types of methods, thus fully meeting the diagnostic challenge of confirming all truly positive cases as positive. Two participants ...

Retrospective evaluation of routine whole genome sequencing of Mycobacterium tuberculosis at the Belgian National Reference Center, 2019.

MTB strains analyzed in 2019 (n = 306). RESULTS: In all cases, the WGS-based procedure was able to identify correctly the MTB species. Compared to MGIT drug susceptibility testing (DST), the sensitivity ...

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