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Vaccine effectiveness against onward transmission of SARS-CoV2-infection by variant of concern and time since vaccination, Belgian contact tracing, 2021.

a re-assessment. METHODS: We estimated VE against transmission of infection (VET) from Belgian contact tracing data for high-risk exposure contacts between 26/0½021 and 14/12/2021 by susceptibility (VE s) and ...

Importance of anti-SARS-CoV-2 assay antigenic composition as revealed by the results of the Belgian external quality assessment (EQA) scheme.

divergent results in the Belgian SARS-CoV-2 serology external quality assessment scheme. Sample IS /17575 was serum originating from a 30 years old male patient. 124 diagnostic laboratories analysed this ...

Poor antibody response to BioNTech/Pfizer COVID-19 vaccination in SARS-CoV-2 naïve residents of nursing homes.

RBD Ab avidity, and neutralizing Ab against SARS-CoV-2 wild type and B.1.351 were assessed at days 0, 21, 28, and 49. RESULTS: SARS-CoV-2 naïve residents had lower Ab responses to BNT162 b2 mRNA ...

Development of a multiplex immunoassay for simultaneous detection of antigens in DTaP vaccines

that could be implemented for routine potency assessment of vaccines. Our work focused on the development of a Luminex-based multiplex assay (four to six-plex assay depending on the number of pertussis ...

Deepening of In Silico Evaluation of SARS-CoV-2 Detection RT-qPCR Assays in the Context of New Variants

future SARS-CoV-2 testing. Given the potential threat of the new variants, it is crucial to assess if they can still be correctly targeted by the primers and probes of the RT-qPCR assays. Our study ...

Identification of flavouring substances of genotoxic concern present in e-cigarette refills

Évaluation des risques et de l'impact sur la santé Risico- en gezondheidsimpactevaluatie Risk and health impact assessment Manuscript versions:  DOI:  https://doi.org/10.1016/j.fct.2020.111864 File:  ...

The EMA PRIME procedure in an accelerated assessment environment for vaccine licensure: Experiences from quality (CMC) assessors. A case study for Ebola vaccine.

Publication Type: Scientific poster, presentation or proceeding Authors: Wim Van Molle; Koen Brusselmans Source: 2020 PDA EUROPE- Driving Biopharmaceutical Innovations & Sustainability BioManufacturing (2020) Health Topics:  Effectiveness and safety o ...

Chemical and toxciological characterization of e-liquid cigarettes

investigated. An adapted risk assessment methodology for intentional inhalation of substances through the e-cigarette was applied. This exercise showed that there is no risk for systemic toxicity related to ...

Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.

(consisting of a total of 30 primers and probe sets) used for SARS-CoV-2 detection and the impact of the virus’ genetic evolution on four of them. The exclusivity of these methods was also assessed using the ...

Identification of Flavouring Substances of Genotoxic Concern Present in E-Cigarette Refills

gezondheidsimpactevaluatie Risk and health impact assessment Full text language:  English Category:  C32 FOS Classification:  3.03 Health sciences ...

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