Search results - 5 results
The phage-encoded PIT4 protein affects multiple two-component systems of Pseudomonas aeruginosa
studied that impacts key virulence factors of the pathogen via interaction with multiple histidine kinases of TCS s. The fundamental insights gained for this protein can therefore serve as inspiration for ...
Pyrogen testing of phage therapeutic products
amoebocyte lysate (LAL) assay and the animal-friendly alternative, the recombinant factor C (rFC) test. However, other (non-endotoxin) pyrogenic substances including compounds of the gram-positive bacterial ...
Validation of an animal-free analytical method for the detection of bacterial endotoxins in human vaccines
3R (2023) Keywords: Endotoxin " vaccine " quality control " recombinant factor c " LAL Abstract: Sciensano, as official medicines control laboratory (OMCL) following ...
Determination of vaccine bacterial endotoxins content by the rFC method
factor c; LAL Abstract: Sciensano, as official medicines control laboratory (OMCL) following “Official Control Authority Batch Release” (OCABR) guidelines, is entitled to check the concentration of ...
Homologous versus heterologous prime-boost COVID-19 vaccination: impact on clinical severity of Omicron among hospitalized COVID-19 patients in Belgium
systems and administrative sources were leveraged to estimate a causal effect. A Directed Acyclic Graph was formalized to identify confounding factors. The target population consisted of adult COVID-19 ...