Search results - 6 results
MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles
cultures. In total 88.6% (172/194) of the samples were correctly identified on the species-level using a cut-off score of 1.8 and 91.75% (178/194) using a cut-off of 1.65. All samples of the Mycobacterium ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
using the approach called RNA tag-Seq, multiple samples were combined in one run, reducing time and cost. Material/methods: For each drug (isoniazid, rifampicin, ethambutol, capreomycin, amikacin, ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
multiple samples were combined in one run, reducing time and cost. Material/methods: For each drug (isoniazid, rifampicin, ethambutol, capreomycin, amikacin, linezolid, moxifloxacin and bedaquilin), twice ...
WIV-ISP's experiences in the use of MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles
the Brüker Database v3.0. For organisms of the Mycobacterium tuberculosis complex, identifications were 100% correct, while the concordance with standard methods was a bit lower for Nontuberculous ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
Background Multidrug resistance of Tuberculosis strains (MDR- TB) are one of the major WHO health concerns. One of the challenges that hampers the effective response to MDR- TB is the long turnaround time of ...
Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid
from the same class. Although delamanid is found to inhibit cell wall synthesis, the expression of genes involved in this process were only mildly affected. In contrast, a clear parallel was found with ...