MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

Last updated on 1-10-2018 by Thibault Degiuli

Scientific poster, presentation or proceeding

English

SCIENSANO

Abstract:

In the last years, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has been increasingly introduced as a valuable method for the identification of bacteria and yeast1. This technique, which generates mass spectra that are compared to reference spectra in databases, is accurate, fast and cost-effective compared to traditional biochemical and molecular techniques. For the identification of Mycobacteria, this method is more challenging due to the special need for inactivation and protein extraction. Although several studies have been published, th…

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