Search results - 25 results
The phage-encoded PIT4 protein affects multiple two-component systems of Pseudomonas aeruginosa
for which the development of novel antibiotics is the most crucial. The pathogen causes both acute and chronic infections, especially in patients who are the most vulnerable. Therefore, efforts are ...
Pyrogen testing of phage therapeutic products
contamination (e.g. cell wall debris) is a major safety concern as these pro-inflammatory agents can cause unwanted clinical reactions with potential detrimental outcome. The most common and potent pyrogens are ...
Validation of an animal-free analytical method for the detection of bacterial endotoxins in human vaccines
assays are suitable for all vaccines tested, although the most appropriate technique of endotoxins quantification depends on the type of vaccine. Health Topics: Effectiveness and safety of vaccines, ...
Spectroscopic approaches for conformity analysis of e-liquids
issue is the presence of additives, illegal according to the European Directive. Some of the most important are caffeine, taurine and vitamin E. Cannabidiol (CBD), which is in the gray zone of the ...
Importance of anti-SARS-CoV-2 assay antigenic composition as revealed by the results of the Belgian external quality assessment (EQA) scheme.
CLIA. All tests against S1 / S2 (Liaison, Diasorin) resulted in a signal above cutoff. Assays against RBD, mostly generate a negative result. An exception are the Wantai SARS-CoV-2 ELISA ’s. All tests ...
Development of a multiplex immunoassay for simultaneous detection of antigens in DTaP vaccines
antibody of the sandwich assay to determine the most favorable combination to use in the multiplex assay (better signal-to-noise ratio). As a proof of concept, the potency of 18 batches from HuB was compared ...
Deepening of In Silico Evaluation of SARS-CoV-2 Detection RT-qPCR Assays in the Context of New Variants
Abstract: For 1 year now, the world is undergoing a coronavirus disease-2019 (COVID-19) pandemic due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The most widely used method for ...
Characterization and hazard identification of substandard and falsified antimicrobials encountered in Belgium
together with anti-malarials, one of the most popular medicines that have been encountered as illegal substandard and falsified (SF) medical products. It has been demonstrated that SF products of these ...
Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market.
Organization (WHO), state that 10% of the medical products in low- and middle-income countries are substandard or falsified (SF). Among them, antibiotics and antimalarials are the most commonly reported since ...
Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market
Among them, antibiotics and antimalarials are the most commonly reported since 2013. Besides the fact that falsification is a crime, the worldwide use of poor quality antimicrobials could result in ...