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In silico methods for chromosome damage
to human health, including for pharmaceuticals. To this extent, a compound’s potential to induce gene mutations as well as chromosome damage needs to be addressed. For chromosome damage, i.e. the ...
Substituted 2,6-bis(benzimidazol-2-yl)pyridines: a novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase.
Drug Resistance, Viral Enzyme Inhibitors Hepacivirus Models, Molecular Mutation Protein Conformation Pyridines RNA Replicase Virus Replication Abstract: 2,6-Bis(benzimidazol-2-yl)pyridine (BBP / CSFA-0) ...
Is there evidence for correct diagnosis in cystic fibrosis registries?
predefined diagnostic criteria. RESULTS: Using as case definition sweat chloride >60mmol/L or 2 CFTR mutations identified, CF diagnosis was not documented in 2.8, 5.7, 6.5 and 21.6% of subjects in the F, B, ...
Intermediate susceptibility to ciprofloxacin among Salmonella enterica serovar Typhi isolates in Lima, Peru31096
Issue 3, Number 970, p.968- 970 (2014) Keywords: 2008 2012 article blood Ceftriaxone Chloramphenicol Ciprofloxacin de electronic gene im IS journal Mutation Peru region Research Research Support ...
Epidemic increase in Salmonella bloodstream infection in children, Bwamanda, the Democratic Republic of Congo33985
Laboratories microbiology Mutation national old Patient patients pattern PATTERNS period Point Mutation PRESENTATION profile Profiles referral Research Research Support Salmonella Salmonella enterica Salmonella ...
Assessment of pfcrt 72-76 haplotypes eight years after chloroquine withdrawal in Kinshasa, Democratic Republic of Congo.
treatment policy in 2002 and an artesunate (AS)-amodiaquine (AQ) combination became the ACT of choice in DRC in 2005. AQ-resistance (AQR) has been reported in several parts of the world and mutations in ...
The TREAT-NMD Duchenne muscular dystrophy registries: conception, design, and utilization by industry and academia
Lynn,S.; Heslop,E.; Gainotti,S.; Taruscio,D.; Kirschner,J.; Verschuuren,J.; Bushby,K.; Beroud,C.; Lochmuller,H. Source: Hum.Mutat., Volume 34, Issue 11, Number 1457, p.1449- 1457 (2013) Keywords: Absence an ...
Infectious Bursal Disease: a complex host-pathogen interaction.
virus, IBDV has a high mutation rate and may thus give rise to viruses with a modified antigenicity or increased virulence, as emphasized during the last decades. The molecular basis of pathogenicity and ...
SYBR®Green qPCR Salmonella detection system allowing discrimination at the genus, species and subspecies levels.
highlighted the importance of using a multi-gene detection system to be able to detect every target strain, even those with deletion or mutation of important genes. Health Topics: Food consumption and food ...
Para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis33991
genetics identification im Institute IS IT journal Laboratories mechanism metabolism Mutation Mycobacterium Mycobacterium tuberculosis Pa PAS pharmacokinetics pharmacology prevent Prodrugs protein Proteins ...