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The pYV plasmid of Yersinia encodes a lipoprotein, YlpA, related to TraT58

Molecular Sequence Data Molecular Weight Mutation pathogenicity Plasmids Print production protein Proteins Research Research Support Residue resistance Restriction Mapping Salmonella Salmonella typhimurium ...

Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.

are prodrugs, for which resistance mechanisms are mainly driven by mutations in the bacterial enzymatic pathway required for their bioactivation. We have developed drug-like molecules that activate ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

resistance mutations, (b) do not distinguish living from dead cells, (c) ignore all intrinsic resistance mechanisms, and (d) ignore the influence of compensatory mutations. Objectives We introduce ...

The BBEMG research program- A multidisciplinary approach in studying long-term effects of ELF-EMF

Health and Food Safety. Verschaeve, L. (2009). Genetic damage in subjects exposed to radiofrequency radiation. Mutat Res. 681(2-3):259-70. Vijayalaxmi, & Obe, G. (2005). Controversial cytogenetic ...

Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set.

Annotation Point Mutation Protein Interaction Maps Abstract: The current wealth of genomic variation data identified at nucleotide level presents the challenge of understanding by which mechanisms amino acid ...

Encompassing new use cases- level 3.0 of the HUPO-PSI format for molecular interactions.

Y Yehudi; Kim Van Roey; S Orchard Source: BMC Bioinformatics, Volume 19, Issue 1 (2018) Keywords: Databases, Protein Humans Mutation Protein Interaction Maps Proteome Proteomics Systems Biology Abstract: ...

Dissecting the molecular evolution of fluoroquinolone-resistant Shigella sonnei.

fluoroquinolone-resistant S. sonnei. We reaffirm that extant resistant organisms belong to a single clonal expansion event. Our results indicate that sequential accumulation of defining mutations (gyrA- S83L, parC- S80I, and ...

Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198.

Egypt before disseminating into Northern, Southern and Western Africa, then to the Middle East, Asia and the European Union. The MDR clone has since accumulated various substitution mutations in the ...

Whole-genome-based phylogenomic analysis of the Belgian 2016-2017 influenza A(H3N2) outbreak season allows improved surveillance.

Organization (WHO) and European Centre for Disease Prevention and Control (ECDC) guidelines is based on combining certain genotypic amino acid mutations and phylogenetic analysis. Next-generation sequencing ...

The small-molecule SMARt751 reverses resistance to ethionamide in acute and chronic mouse models of tuberculosis.

and chronic TB. SMAR t751 also restored full efficacy of ethionamide in mice infected with strains carrying mutations in the gene, which cause ethionamide resistance in the clinic. SMAR t751 was shown ...

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