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Search results - 13 results
Pyrogen testing of phage therapeutic products
endotoxins, components of the cell wall of gram-negative bacteria which are released upon bacterial lysis. In our routine phage quality control (QC) workflow, endotoxins are quantified using the Limulus ...
Development of strain-level shotgun metagenomics approaches to detect and characterize microbiological contaminants in the context of food safety
enrichment. All protocols that have been proposed have been chosen to be as close as possible to the ones currently used in the reference laboratories so they can be adapted to be used in routine in the future. ...
The GEONs API-fingerprint program: Tackling falsifications of APIs
casualties happened when altered API s escaped detection in routine analytical testing. Any form of tampering the content or information about the content might affect the quality of the API, the finished ...
Development of a data-intensive centralized system for surveillance and outbreak investigation of bacterial pathogens using whole-genome sequencing
sequencing (WGS), the sequencing of (nearly) complete genomes, has had an enormous impact on almost all fields of biology. However, its successful integration into routine public health practice has lagged ...
Development of a multiplex immunoassay for simultaneous detection of antigens in DTaP vaccines
Virtual (2021) Keywords: 3R Vaccine Potency Abstract: Routine batch quality testing before vaccine release, notably for potency evaluation, still relies on animal use for several animal and human vaccines. ...
Strategies to detect unauthorized GMO in the food and feed chain (PhD thesis)
https://www.sciensano.be/en/biblio/strategies-detect-unauthorized-gmo-food-and-feed-chain-phd-thesis
enforcement laboratories is becoming complex due mainly to the increasing number and diversity of GMO. To cope with the problematic of EU unauthorized GMO, this PhD aims to improve and strengthen the existing ...
Strategies to detect unauthorized genetically modified organisms in food and feed chain
(EU). However, the implementation of these legislations by the enforcement laboratories is becoming complex due mainly to the increasing number and diversity of GMO. To cope with the problematic of EU ...
Development and implementation of a transversal NGS & bioinformatics platform at the Belgian Institute of Public Health
Databases Development Diagnosis effective Emergencies Emergency expertise genomic Genomics Guidelines health HEALTH POLICIES HEALTH POLICY implementation Institute interaction IS KNOWLEDGE Laboratories Life ...
Batch release of vaccines in Europe: from method transfer to first commercial batch available on the market. Straightforward approach that requires a proactive mind-set of the manufacturer.
medicinal products or medicinal products derived from human blood or plasma by an Official Medicines Control Laboratory (OMCL) before these can be marketed. The competent authorities issue a Batch Release ...
First Belgian national EQA for special stains in histopathology
laboratories were encouraged to process the samples within the laboratory’s regular workloadof patient specimens, using their routine methods.Methods:A panel of two formalin-fixed and paraffin-embedded tissue ...