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Strain-level characterization without culture enrichment? Easing and accelerating outbreak investigation using shotgun metagenomics facilitated with nanopore adaptive sampling

analysing the DNA of the sample, it can identify the presence of various pathogens to the strain level. Moreover, adaptive sampling is a new tool proposed during nanopore sequencing to target certain DNA ...

Pyrogen testing of phage therapeutic products

these last years, with treatments provided to more than 100 patients, against more than 10 different bacterial species. Therapeutic phage products are produced  in a bacterial host strain, hence pyrogen ...

What do we request for production and quality control of CHIM strains.Should it be GMP or is adherence to GMP acceptable?

Publication Type: Scientific poster, presentation or proceeding Authors: Wim Van Molle Source: Ethical Approval for CHIM Clinical Trial Protocols, IABS, Brussels, Belgium (2023) Service:  Qualité des vaccins et produits sanguins Kwaliteit van vaccins en b ...

Shotgun metagenomics for strain-level food-borne outbreak investigation

Publication Type: Scientific poster, presentation or proceeding Authors: Florence E Buytaers Source: FoodMicro (2022) Service:  Activités transversales en génomique appliquée Transversale activiteiten in toegepaste genomica Transversal activities in appli ...

Shotgun metagenomics as a ONE Health tool for better protecting human health

laboratories, however without isolation and in a shorter time-frame. This could be achieved to the strain level even in samples with several E. coli strains. The method was also used to solve a Salmonella ...

Characterization of Clostridium tetani seed strains – DNA seq/RNA seq/ targeted proteomics

Publication Type: Scientific poster, presentation or proceeding Authors: Jeroen Pennings; Celine Vanhee Source: VAC2VAC annual meeting (2021) Health Topics:  Effectiveness and safety of vaccines, medicines and health products- Quality of medical laborator ...

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