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Pre-registration efficacy study of a novel marker vaccine against classical swine fever on Maternally Derived Antibody negative (MDA-) target animals.

Publication Type: Peer reviewed scientific article Authors: Levai, R; Barna, T; Fábián, K; Blome, S; Belák, K; Bálint, Á; F. Koenen; Kulcsar, G; Farsang, A Source: Biologicals, Volume 43, Issue 2, p.92-9 (2015) Keywords: Animals Antibodies, Viral Biomarke ...

Antimicrobial resistance and population structure of Staphylococcus epidermidis recovered from pig farms in Belgium.

Abstract: Pigs are known to harbour a variety of staphylococcal bacteria, including Staphylococcus epidermidis, in the upper respiratory tract. The aim of the present study was to determine the prevalence, ...

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.

template-primer duplex. Elucidation of a crystal structure of the inhibitor bound to CVB3 3Dpol confirmed the RNA-binding channel as the target for GPC- N114. Docking studies of the compound into the crystal ...

Campylobacter carcass contamination throughout the slaughter process of Campylobacter-positive broiler batches.

chilling, respectively. This finding indicates that certain slaughterhouses are able to better control Campylobacter contamination than others. Overall, the present study focuses on the descriptive analysis ...

Evaluation of adaptive immune responses and heterologous protection induced by inactivated bluetongue virus vaccines.

virus is possible, as has been shown in several European countries. New serotypes have emerged, however, for which there are no specific commercial vaccines. This study addressed whether heterologous ...

Human biomonitoring of multiple mycotoxins in the Belgian population: Results of the BIOMYCO study.

assessment at individual level. For this reason, the BIOMYCO study was designed to assess mycotoxin exposure in Belgian adults and children using urinary biomarkers of exposure. Morning urine was gathered in ...

A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus.

alternative to pre-emptive culling or emergency vaccination we further explore the possibility to use antiviral drugs in the event of an FMD outbreak. In the present study, we tested the in vitro cytotoxicity ...

Study of the virulence of serotypes 4 and 9 of African horse sickness virus in IFNAR(-/-), Balb/C and 129 Sv/Ev mice.

belongs to the family Reoviridae, genus Orbivirus. Recent studies have focused on the interferon-α/β receptor knock-out mice (IFNAR (-/-)) as a small animal laboratory for the development of AHSV vaccines. ...

Proof of concept for the inhibition of foot-and-mouth disease virus replication by the anti-viral drug 2'-C-methylcytidine in severe combined immunodeficient mice.

with serotype A FMD virus and treated for five consecutive days with 2’ CMC. All 15 treated mice remained healthy until the end of the study at 14 days post-infection (dpi). At that time, viral RNA was ...

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