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Using a combination of short- and long-read sequencing to investigate the diversity in plasmid- and chromosomally encoded extended-spectrum beta-lactamases (ESBLs) in clinical Shigella and Salmonella isolates in Belgium

Publication Type: Peer reviewed scientific article Authors: Berbers, Bas; Vanneste, Kevin; Roosens, Nancy H. C. J.; Marchal, Kathleen; Pieter-Jan Ceyssens *; De Keersmaecker, Sigrid C. J. Source: Microbial Genomics, Volume 9, Issue 1 (2023) Health Topics: ...

Retrospective surveillance of viable Bacillus cereus group contaminations in commercial food and feed vitamin B2 products sold on the Belgian market using whole-genome sequencing

whole-genome sequencing (WGS) and subsequently characterized in terms of sequence type (ST), virulence gene profile, antimicrobial resistance (AMR) gene profile, plasmid content, and phylogenomic relationships. ...

A genomic appraisal of invasive Salmonella Typhimurium and associated antibiotic resistance in sub-Saharan Africa.

ST313- L2 likely emerged in the Democratic Republic of Congo around 1980 and further spread in the mid 1990s. We observed plasmid-borne as well as chromosomally encoded fluoroquinolone resistance ...

A global genomic analysis of Salmonella Concord reveals lineages with high antimicrobial resistance in Ethiopia.

demonstrate the presence of AMR markers integrated in structurally diverse IncHI2 and IncA/ C2 plasmids, and/or the chromosome. Molecular surveillance of pathogens such as S. Concord supports the understanding ...

First Belgian Report of Ertapenem Resistance in an ST11 Klebsiella Pneumoniae Strain Isolated from a Dog Carrying blaSCO-1 and blaDHA-1 Combined with Permeability Defects

ertapenem, third-generation cephalosporins and fluoroquinolones. A hybrid approach, combining long- and short-read sequencing, was employed for in silico plasmid characterization, multi-locus sequence typing ...

Genomic epidemiology of persistently circulating MDR Shigella sonnei strains associated with men who have sex with men (MSM) in Belgium (2013–19)

various incompatibility (Inc)-type plasmids, the SpA plasmid and ESBL  genes. CONCLUSIONS: In Belgium, S. sonnei isolates from men are much more likely to be resistant to important first-line antibiotics ...

Population Analysis of O26 Shiga Toxin-Producing Causing Hemolytic Uremic Syndrome in Italy, 1989-2020, Through Whole Genome Sequencing.

accessory genomic fraction. A novel O26 STEC clone belonging to Sequence Type (ST) 29 and harboring, and plasmid-borne genes has emerged and spread in Europe since the mid-1990s, while another ST29 clone ...

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