National Reference Center (NRC) for Bordetella pertussis

Important communication regarding PCR for Bordetella (04/10/2023)

Problem

  • UTM swabs contain antibiotics, which makes culture (as part of the NRCs activities) impossible.
  • Copan discovered in 2021 that the raw materials used to produce the eSwab® collection material contain small quantities of non-viable Bordetella parapertussis nucleic acid residues. As a result, false positive results can be obtained for the detection of Bordetella parapertussis (low positive with high Ct) when sensitive molecular techniques are used.

Action

Preferably do not use eSwab® for Bordetella PCR, but swabs and transport media from other manufacturers, or preferably collect the nasopharyngeal sample by washing (with a syringe), rinsing (with a sterile nose bulb) or aspiration (with vacuum aspiration).

General information

  1. Symptoms from whooping cough
  2. Sampling of nasopharyngeal material

Overview analysis and facturation

Analysis Labo Facturation
Confirmation of molecular detection and culture of Bordetella pertussis NRC UZ Brussels No
PCR and culture Medical microbiology labo UZ Brussels

Yes, invoiced directly to RIZIV/INAMI, if article 24bis criteria applicable

Yes, to the patient or laboratory of origin, if criteria not applicable

Serology NRC Sciensano

No (if it is a diagnostic test)

Yes, to the patient or laboratory of origin (if it is an immune status assessment)

* you can contact a routine laboratory of your choice

Helpful links:

At the bottom of this page, you can find the NRC reports/epidemiological reports

You can consult the epidemiological surveillance reports also at: Health topic Whooping cough, Health topic Vaccine-preventable diseases.

Responsible laboratories

Coordinator

Associated

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