Search results - 23 results

The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.

each mutation. Findings: 15,667 associations were computed for 13,211 unique mutations linked to one or more drugs. 1,149/15,667 (7·3%) mutations were classified as associated with phenotypic resistance and ...

Multicentre study on the reproducibility of MALDI-TOF MS for nontuberculous mycobacteria identification.

procedure or to MALDI- TOF system status in each centre. In conclusion, MALDI- TOF showed to be a highly reproducible method and suitable for its implementation for NTM  identification. Health Topics:  ...

Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.

billion people are infected with, leading to 10 million new cases of active tuberculosis and 1.5 million deaths annually. Universal access to drug susceptibility testing (DST) has become a World Health ...

Strong increase of true and false positive mycobacterial cultures sent to the National Reference Centre in Belgium, 2007 to 2016.

at the NRC, highlighting the importance of sample decontamination/transport and equipment calibration in peripheral laboratories. Health Topics:  Tuberculosis Tuberculose Tuberculose Manuscript ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

Pieter-Jan Ceyssens Source: 39th Annual Congress of the European Society of Mycobacteriology, Issue ESM, Dresden, Germany (2018) Keywords: drug susceptibility testing Mycobacterium tuberculosis Health Topics:  ...

Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study.

1060 specimens were tested using four laboratory assays. The number of specimens per batch varied from one to 60; a total of 64 recordings were performed. Theoretical hands-on times per specimen (TTPS) ...

A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.

shared mutation of tlyA is a drug resistance mutation and phylogenetic marker, the first of its kind in M tuberculosis sensu stricto. FUNDING: The Swiss Federal Office of Public Health, the University of ...

Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.

at least rifampicin, isoniazid, any fluoroquinolone and one of the injectable anti-tuberculosis drugs, remains a worldwide public health threat. Among repurposed drugs empirically used for XDR- TB ...

Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection

Letesson, Jean-Jacques; David Fretin; Rigouts, Leen; Elie Chapeira; Vanessa Mathys; Saegerman, Claude; Huygen, Kris; Cloeckaert, Axel Source: PLOS ONE, Volume 12, Issue 2 (2017) Keywords: Paratuberculosis ...

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