Search results - 13 results

Pyrogen testing of phage therapeutic products

contamination (e.g. cell wall debris) is a major safety concern as these pro-inflammatory agents can cause unwanted clinical reactions with potential detrimental outcome. The most common and potent pyrogens are ...

Development and validation of a targeted LC-MS/MS quantitation method to monitor cell culture expression of tetanus neurotoxin during vaccine production

Publication Type: Peer reviewed scientific article Authors: Antoine Francotte; Raphael Esson; Eric Abachin; Melissa Vanhamme; Alexandre Dobly; Bruce Carpick; Sylvie Uhlrich; Jean-François Dierick; Celine Vanhee Source: Talanta, Volume 236 (2022) Health To ...

A new approach to define acceptance limits for hematology in external quality assessment schemes.

 organizers. METHODS: Eight EQAS organizers from seven European countries provided their hematology survey results from 2010 to 2012 for red blood cells (RBC), hemoglobin, hematocrit, mean corpuscular volume ...

Zona pellucida gene mRNA expression in human oocytes is related to oocyte maturity, zona inner layer retardance and fertilization competence.

p.292-303 (2017) Abstract: STUDY QUESTION: Do the mRNA expression levels of zona pellucida (ZP) genes, ZP1, 2, 3 and 4 in oocyte and cumulus cells (CC) reveal relevant information on the oocyte? SUMMARY ...

The role of methylation, DNA polymorphisms and microRNAs on HLA-G expression in human embryonic stem cells.

Publication Type: Peer reviewed scientific article Authors: Verloes, A; Spits, C; Vercammen, M; Geens, M; LeMaoult, J; Sermon, K; Wim Coucke; Van de Velde, H Source: Stem Cell Res, Volume 19, ...

Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.

Adjuvants, Immunologic Animals Antigens, Bacterial Cell Wall Humans Immunity, Innate Lectins, C-Type Models, Animal Mycobacterium Pathogen-Associated Molecular Pattern Molecules Protein Binding Signal ...

Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.

Issue 9, p.2215-29 (2016) Keywords: Carcinogens Cell Line, Tumor Computational Biology Dose-Response Relationship, Drug Gene Expression Profiling Gene Expression Regulation Genome-Wide Association Study ...

In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics.

information. In the EU, dermal absorption has to be assessed in vitro since the Cosmetic Regulation 1223/2009/ EC forbids the use of animals. To obtain human-relevant data, a Franz diffusion cell protocol was ...

In vitro Dermal Absorption: Sample Application and Seal Quality in a Franz Diffusion Cell System.

Publication Type: Peer reviewed scientific article Authors: Bart Desmedt; Patricia Courselle; De Beer, Jacques O; Rogiers, Vera; Eric Deconinck; De Paepe, Kristien Source: Skin Pharmacol Physiol, Volume 28, Issue 5, p.245-9 (2015) Keywords: Administration ...

External Quality Assessment for the Detection of Chlamydia trachomatis in Urine Using Molecular Techniques in Belgium.

sexually transmitted bacterial disease worldwide. C. trachomatis is an intracellular bacterium and its growth in vitro requires cell culture facilities. The diagnosis is based on antigen detection and more ...

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