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Pyrogen testing of phage therapeutic products
this work, we discuss and compare the applicability of the LAL, rFC and MAT tests for pyrogen testing of clinical grade phage products based on the analysis of various productions manufactured by the ...
The GEONs API-fingerprint program: Tackling falsifications of APIs
API testing within the network is limited, compared to the surveillance of finished products. To tackle the issue of falsified API detection the API-working group (API- WG) of the GEON organizes ...
Vaccine effectiveness against onward transmission of SARS-CoV2-infection by variant of concern and time since vaccination, Belgian contact tracing, 2021.
compared to viral vector vaccines: 66% and 80% for Ad26COV2.S and ChAdOx1 respectively (Alpha, 0-50 days after vaccination). Delta was associated with a 40% increase in odds of transmission and a decrease of ...
Incidence and Risk Factors of COVID-19 Vaccine Breakthrough Infections: A Prospective Cohort Study in Belgium.
CI 11.2-11.3)/100 person years. Vaccination with Ad26. COV2.S (HR1.54, 95% CI 1.52-1.56) or ChAdOx1 (HR1.68, 95% CI 1.66-1.69) was associated with a higher risk of a breakthrough infection compared to ...
Poor antibody response to BioNTech/Pfizer COVID-19 vaccination in SARS-CoV-2 naïve residents of nursing homes.
detectable neutralizing Ab to the B.1.351 variant. In contrast, SARS-CoV-2 infected residents had high responses to mRNA vaccination, with Ab levels comparable to infected staff. Cluster analysis revealed that ...
Development of a multiplex immunoassay for simultaneous detection of antigens in DTaP vaccines
antibody of the sandwich assay to determine the most favorable combination to use in the multiplex assay (better signal-to-noise ratio). As a proof of concept, the potency of 18 batches from HuB was compared ...
Comparative Evaluation of Lumpy Skin Disease Virus-Based Live Attenuated Vaccines.
purpose of this study to compare five homologous live attenuated LSDV vaccines (LSDV LAV) in a standardized setting. All five LSDV LAV s studied were able to protect against a challenge with virulent LSDV. ...
Characterization and hazard identification of substandard and falsified antimicrobials encountered in Belgium
dissolution methods were adopted from the United States Pharmacopeia (USP) [3-4]. Moreover, the dissolution profiles of SF antimicrobials were compared to the ones of their genuine counterparts. In general, ...
A new approach to define acceptance limits for hematology in external quality assessment schemes.
Hemoglobins Humans Leukocytes Quality Assurance, Health Care Abstract: BACKGROUND: A study performed in 2007 comparing the evaluation procedures used in European external quality assessment schemes (EQAS) for ...
The use of Stationary Phase Optimized Selectivity Liquid Chromatography for the development of herbal fingerprints to detect targeted plants in plant food supplements.
suspicious supplements seized by the authorities. For three of the five plants a more specific fingerprint was obtained, compared to the ones developed on traditional columns described in literature. It could ...