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In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.

ERAV surrogate models reported here can be manipulated in BSL-2 laboratories and may facilitate studies to unravel the mechanism of action of novel FMDV  inhibitors. Health Topics:  Animal health ...

Impact of availability of guidelines and active surveillance in reducing the incidence of ventilator-associated pneumonia in Europe and worldwide

BACKGROUND: To analyse whether the availability of written standards for management of mechanically ventilated patients and/or the existence of a surveillance system for cases of ventilation-associated ...

Cytokine and immunoglobulin isotype profiles during CP7_E2alf vaccination against a challenge with the highly virulent Koslov strain of classical swine fever virus.

Vaccination Vaccines, Attenuated Viral Vaccines Abstract: CP7_E2alf is a promising marker vaccine candidate against classical swine fever (CSF). To better understand the mechanisms of protection, cytokine and ...

Genotoxicity evaluation of nanosized titanium dioxide, synthetic amorphous silica and multi-walled carbon nanotubes in human lymphocytes.

instead of assuming a common mechanism and equal genotoxic effects for a set of similar NM s. Health Topics:  Animal health Category:  A1 FOS Classification:  4.03 Veterinary science ...

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK651

electronic enzymology function functions Genetic genetics Glioblastoma growth Hand Hematology hospital Human Humans im in vivo IS IT journal Lipogenesis mechanism mechanisms medical metabolism Metformin mice ...

Interaction of Aspergillus fumigatus conidia with Acanthamoeba castellanii parallels macrophage-fungus interactions.

common inhabitants of soil. Mechanisms of A. fumigatus to circumvent the amoeba’s digestion may facilitate overcoming the vertebrate macrophage defence mechanisms. We performed co-culture experiments using ...

Infectious Bursal Disease: a complex host-pathogen interaction.

Recent progress in the field of avian immunology has allowed a better knowledge of the immunological mechanisms involved in the disease but also should give improved tools for the measurement of ...

4-Methyl-amphetamine: a health threat for recreational amphetamine users.

the observed toxicity. Other mechanisms of toxicity are put forward in this paper as well. To conclude, the observed toxicity is most likely the result of the combined dopaminergic activity of ...

Para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis33991

genetics identification im Institute IS IT journal Laboratories mechanism metabolism Mutation Mycobacterium Mycobacterium tuberculosis Pa PAS pharmacokinetics pharmacology prevent Prodrugs protein Proteins ...

Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect.

phthalates and BPA, however not required for obesogenic effects induced by Tonalide, indicating the role of other obesogenic mechanisms for this compound. Health Topics:  Endocrine disruptors Perturbateurs ...

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