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Virological surveillance of influenza in Belgium, season 2019-2020
previous seasons. None of the analyzed strains presented mutations known to be associated to resistance to antivirals neuraminidase inhibitors (Oseltamivir et Zanamivir). Health Topics: Health and disease monitoring ...
In silico methods for chromosome damage
to human health, including for pharmaceuticals. To this extent, a compound’s potential to induce gene mutations as well as chromosome damage needs to be addressed. For chromosome damage, i.e. the ...
Annual Report Belgian Cystic Fibrosis Registry 2018
registry, 18 years ago, 39.0% were adults, and the median age was 14.9 years, showing changes in demographics over the years. 45.8% of the patients are homozygous for the F508 del mutation and 38.0% are F508 ...
Annual Report Belgian Cystic Fibrosis Registry 2017
18 years ago, 39.0% were adults, and the median age was 14.9 years. 46.4% of the patients are homozygous for the F508 del mutation and 39.1% are F508 del heterozygous. The main reasons for diagnosis of ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
the knowledge on resistance mutations which is limited for especially 2nd-line and new drugs, (b) do not distinguish living from death cells, (c) ignore all intrinsic resistance mechanisms like efflux ...
Comparative genomics of quinolone-resistant and susceptible Campylobacter jejuni of poultry origin from major poultry producing European countries (GENCAMP)
isolates clustered in four main clusters. All trees revealed that the isolates were clustered according to the presence/absence of the gyrA mutations causing fluoroquinolone resistance and ST-types. The ...
Annual report Belgian Cystic Fibrosis Registry 2016
can be compared to the start of the registry 17 years ago when 39.0% were adults with a median age of 14.9 years. 46.7% of the patients are homozygous for the F508 del mutation while 37.0% are F508 del ...
European Antimicrobial Resistance Surveillance Network (EARS-Net Belgium)- Report 2017 (Data up to and including 2016)
them. Resistance arises in three ways: natural (intrinsic) resistance in certain types of bacteria, or acquired via either genetic mutation, or by horizontal gene transfer. The European Antimicrobial ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
(480 000 new cases), impeding the treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations. However, transcriptional analyses can be ...