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Development, validation, and application of a multimatrix UHPLC-MS/MS method for quantification of Datura-type alkaloids in food
spectrometry (UHPLC- MS / MS) method was developed and validated for the determination of tropane alkaloids (TA s), atropine and scopolamine, in a variety of food products. The sample preparation of cereal-based ...
Belgian recommendations for analytical verification and validation of immunohistochemical tests in laboratories of anatomic pathology
a quality management system in anatomic pathology laboratories has been reviewed to meet this demand and additionally to prepare the laboratories for the EU — IVD revised regulations (IVDR). This paper ...
Multidimensional chromatographic fingerprinting combined with chemometrics for the identification of regulated plants in suspicious plant food supplements
× time points) were used for selection of orthogonal wavelengths by conducting a correlation analysis. After preparation of triturations, recording of the fingerprints and creation of datasets (corrected ...
The Development and Validation of a Targeted LC-HRAM-MS/MS Methodology to Separate and Quantify p-Synephrine and m-Synephrine in Dietary Supplements and Herbal Preparations
Publication Type: Peer reviewed scientific article Authors: Vanhee, Celine; Barhdadi, Sophia; Kamugisha, Angélique; Van Mulders, Tanika; Vanbrusselen, Kevin; Willocx, Marie; Eric Deconinck Source: Separations, Volume 10, Issue 8 (2023) Health Topics: Hea ...
Regulatory expectations on the use of vaccine reference standards for maintaining product quality.
should meet all requirements regarding safety and efficacy before its release to the market. The use of (international) reference standards or reference preparations plays a key role in assay validation ...
COVID-19 pandemic response in the Meuse-Rhine Euroregion: methods, participation and recommendations of a longitudinal cross-border study
regulations Meuse-Rhine Euroregion Pandemic preparedness Pandemic response Prospective longitudinal studies SARS-CoV-2 Abstract: BACKGROUND: Comparative data collection in transborder areas can contribute to ...
Spectroscopic approaches for conformity analysis of e-liquids
in two and one of both aliquots was spiked with the targeted additives in realistic concentrations. After sample set preparation, mid-infrared, near-infrared and Raman spectra were recorded for all ...
Predicting the severity of the grass pollen season and the effect of climate change in Northwest Europe
following are major questions often posed by those with allergic rhinitis: How should I prepare for the forthcoming season? How will the season’s severity develop over the years? No country yet provides clear ...
Development of strain-level shotgun metagenomics approaches to detect and characterize microbiological contaminants in the context of food safety
sample preparation methods allowed to obtain a full characterization to strain level of the spiked strain in the beef sample, carrying another non-pathogenic strain of E.coli. The simplest protocol was ...
Targeted High-Throughput Sequencing Enables the Detection of Single Nucleotide Variations in CRISPR/Cas9 Gene-Edited Organisms
containing different percentages of a GE rice line carrying a single adenosine insertion in OsMADS26 were prepared and analyzed. The SNV of interest in samples containing the GE rice line could successfully be ...