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Recombinant LSDV Strains in Asia: Vaccine Spillover or Natural Emergence?
Publication Type: Peer reviewed scientific article Authors: Frank Vandenbussche; Elisabeth Mathijs; Wannes Philips; Saduakassova, Meruyert; Ilse De Leeuw; Sultanov, Akhmetzhan; Andy Haegeman; Kris De Clercq Source: Viruses, Volume 14, Issue 7 (2022) Healt ...
Poor antibody response to BioNTech/Pfizer COVID-19 vaccination in SARS-CoV-2 naïve residents of nursing homes.
vaccination than naïve staff. These poor responses involved lower levels of IgG to all spike domains, lower avidity of RBD IgG, and lower levels of Ab neutralizing the vaccine strain. No naïve resident had ...
WGS- versus ORF5-Based Typing of PRRSV: A Belgian Case Study.
circulating PRRSV strains by means of sequencing is crucial for developing adequate control strategies. Most genetic studies only target the highly variable open reading frame (ORF) 5, for which an extensive ...
Metagenomic sequencing determines complete infectious bronchitis virus (avian Gammacoronavirus) vaccine strain genomes and associated viromes in chicken clinical samples.
genome with 99.95% nucleotide identity to vaccine strain 793B. In addition, substantial read counts (16% of viral reads) allowed the assembly of a near-complete chicken astrovirus genome, while lower read ...
Retrospective evaluation of routine whole genome sequencing of Mycobacterium tuberculosis at the Belgian National Reference Center, 2019.
MTB strains analyzed in 2019 (n = 306). RESULTS: In all cases, the WGS-based procedure was able to identify correctly the MTB species. Compared to MGIT drug susceptibility testing (DST), the sensitivity ...
Strategy to Develop and Evaluate a Multiplex RT-ddPCR in Response to SARS-CoV-2 Genomic Evolution.
SARS-CoV-2 strains that were representative for the circulating strains around the world. The RT-ddPCR platform was selected as it presented several advantages to detect and quantify SARS-CoV-2 RNA in clinical ...
Controlled Human Infection Studies: Proposals for guidance on how to design, develop and produce a challenge strain.
Publication Type: Peer reviewed scientific article Authors: Isabelle Bekeredjian-Ding; Jean-Hugues Trouvin; Hilde Depraetere; Carine La; Akamol E Suvarnapunya; Alan Bell; Alex Mann; Pauline Meij; Jeffrey M Bethony; Linda Schellhaas; Nazziwa, Winfred Badan ...
Characterization of Genetically Modified Microorganisms Using Short- and Long-Read Whole-Genome Sequencing Reveals Contaminations of Related Origin in Multiple Commercial Food Enzyme Products.
comparative analyses showed that the isolates likely originate from the same parental GM strain. This study highlights the added value of a hybrid WGS approach for accurate genomic characterization of GMM ...
Reduced humoral immune response after BNT162b2 coronavirus disease 2019 messenger RNA vaccination in cancer patients under antineoplastic treatment.
booster) and in vitro SARS-CoV-2 50% neutralization titers (NT50) toward the wild-type Wuhan strain were analyzed 28 days after the booster. RESULTS: Local and systemic adverse events (AE s) were mostly mild ...
Characterization of Clostridium tetani seed strains – DNA seq/RNA seq/ targeted proteomics
Publication Type: Scientific poster, presentation or proceeding Authors: Jeroen Pennings; Celine Vanhee Source: VAC2VAC annual meeting (2021) Health Topics: Effectiveness and safety of vaccines, medicines and health products- Quality of medical laborator ...