Search results - 58 results

Ethical approval for controlled human infectious model clinical trial protocols- A workshop report.

Shobana; Neels, Pieter Source: Biologicals, Volume 85 (2024) Keywords: Drug Development Healthy Volunteers Humans Research Design Abstract: Controlled Human Infectious Model studies (CHIM) involve ...

Pollutant exposure and myocardial injury: Protocol and progress report for a toxicological systematic mapping review.

while CVD incidence rises steadily with the aging population. Although numerous experimental studies are now available, the mechanisms through which lifetime exposure to environmental pollutants can ...

Federated causal inference based on real-world observational data sources: application to a SARS-CoV-2 vaccine effectiveness assessmentAbstractIntroductionMethodsResultsConclusions

successfully demonstrated within the BY- COVID project. Different Findable, Accessible, Interoperable and Reusable (FAIR) research objects were produced, such as a study protocol, a data management plan, ...

The impact of the COVID-19 pandemic on the mental health of healthcare workers: study protocol for the COVID-19 HEalth caRe wOrkErS (HEROES) study

a negative impact on the mental health of the healthcare workforce. In this paper, we summarize the protocol of the COVID-19 HE alth caRe wOrkErS (HEROES) study, an ongoing, global initiative, aimed to ...

Evaluating the health and health economic impact of the COVID-19 pandemic on delayed cancer care in Belgium: A Markov model study protocol

quality-adjusted life year losses between the pre- COVID-19 situation and the COVID-19 pandemic in Belgium. Input parameters were derived from published studies (transition probabilities, utilities and indirect ...

Burden of disease attributable to risk factors in European countries: A scoping literature review

misinterpretations thus improving comparability among estimates. REGISTRATION: The study protocol has been registered on PROSPERO, CRD42020177477 (available at: https://www.crd.york.ac.uk/ PROSPERO /). Health Topics:  ...

Protocol for a systematic review and meta-analysis of the diagnostic test accuracy of host and HPV DNA methylation in cervical cancer screening and management.

a test to diagnose cervical intraepithelial neoplasia (CIN); we present a protocol to evaluate the accuracy of methylation markers to detect high-grade CIN and cervical cancer. METHODS AND ANALYSIS: We ...

Social inequalities and long-term health impact of COVID-19 in Belgium: protocol of the HELICON population data linkage

Belgium Cohort Studies COVID-19 COVID-19 Testing Humans Pandemics SARS-CoV-2 Abstract: INTRODUCTION: Data linkage systems have proven to be a powerful tool in support of combating and managing the COVID-19 ...

Development of strain-level shotgun metagenomics approaches to detect and characterize microbiological contaminants in the context of food safety

characterization had only been achieved in a handful of studies, and had not been proven possible when more than one strain of the same species were present. Moreover, the genome obtained from metagenomics sequences ...

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