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Determinants of the Bovine Leukemia Virus Envelope Glycoproteins Involved in Infectivity, Replication and Pathogenesis.
TM is postulated to be essential, some proviruses expressing fusion-deficient envelope proteins unexpectedly replicate at wild-type levels. Surprisingly also, a conserved N-linked glycosylation site of ...
Even attenuated bovine leukemia virus proviruses can be pathogenic in sheep.
Publication Type: Peer reviewed scientific article Authors: Florins, Arnaud; Gillet, Nicolas; Boxus, Mathieu; Pierre Kerkhofs; Kettmann, Richard; Willems, Luc Source: J Virol, Volume 81, Issue 18, p.10195-200 (2007) Keywords: Amino Acid Motifs Animals Cat ...
Complete suppression of viral gene expression is associated with the onset and progression of lymphoid malignancy: observations in Bovine Leukemia Virus-infected sheep.
nontransformed counterparts. RESULTS: In the first animal, we observed the emergence of a genetically modified provirus simultaneously with leukemia onset. We found a Tax-mutated (TaxK303) replication-deficient provirus in the ...
Suppression of viral gene expression in bovine leukemia virus-associated B-cell malignancy: interplay of epigenetic modifications leading to chromatin with a repressive histone code.
Proviruses Sheep Abstract: Ovine leukemia/lymphoma resulting from bovine leukemia virus infection of sheep offers a large animal model for studying mechanisms underlying leukemogenesis. Silencing of viral ...
Reduced proviral loads during primo-infection of sheep by Bovine Leukemia virus attenuated mutants.
Plasmids polymerase chain reaction Promoter Regions, Genetic Proviruses Quaternary Ammonium Compounds Sheep Sheep Diseases Terminal Repeat Sequences Viral Load Abstract: BACKGROUND: The early stages ...
Attenuation of bovine leukemia virus by deletion of R3 and G4 open reading frames.
Issue 24, p.11532-6 (1994) Keywords: Animals Base Sequence DNA Primers Gene Expression Regulation, Viral Genes, Viral Leukemia Virus, Bovine Molecular Sequence Data Proviruses Retroviridae Proteins RNA, ...