Résultats de la recherche - 312 results

Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals

Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Matthew Meier; Carole Yauk; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; ...

Oncolytic Viruses: An Inventory of Shedding Data from Clinical Trials and Elements for the Environmental Risk Assessment.

replication-defective viral vectors commonly used in gene therapy or vaccination. To our knowledge, this article presents the most extensive and up-to-date review of shedding data reported with OV employed in clinics. ...

Reducing the Burden on Animals and the Heart: An Evidence-Based Approach to Cardiotoxicity Assessment

Martin Paparella Source: 12th World Congress on Alternatives and Animal Use in the Life Sciences, Nigara falls, Canada (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to ...

A Systematic Review on Pollutant Induced Cardiotoxicity: Providing a Toxicological Foundation for NAM Development and Regulatory Acceptance

Ritskes-Hoitinga; R. Gehring Source: 12th World Congress on Alternatives and Animal Use in the Life Sciences, Nigara falls, Canada (2023) Keywords: Cardiotoxicity pollutants systematic review toxicological evidence ...

Cardiotoxicity of chemicals: Current regulatory guidelines, knowledge gaps, and needs.

gezondheidsimpactevaluatie Risk and health impact assessment Manuscript versions:  DOI:  https://sciensano.be/en/10.14573/altex.2301121 Version:  Published Full text access:  Public Access Full text language:  English ...

Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.

Publication Type: Peer reviewed scientific article Authors: Thienpont, Anouck; Verhulst, Stefaan; Van Grunsven, Leo A; Rogiers, Vera; Vanhaecke, Tamara; Birgit Mertens * Source: ALTEX, Volume 40, ...

Release of Nano-objects, their aggregates and agglomerates from Masks: ambitions and scientific objectives of the RENAAME project

Publication Type: Scientific poster, presentation or proceeding Authors: F.-X. Ouf; F. Gaie-Levrel; S. Chazelet; G. Favre; N. Feltin; V. Ferré; V. Godefert; J. Mast; J. Noireaux; S. Pacault; X. ...

Cardiotoxicity of chemicals: Current regulatory guidelines, knowledge gaps, and needs.

https://sciensano.be/en/10.14573/altex.2301121 Version:  Published Full text access:  Public Access Full text language:  English Category:  Peer-reviewed scientific articles FOS Classification:  3.05 Other medical sciences ...

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