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Résultats de la recherche - 42 results
Poor antibody response to BioNTech/Pfizer COVID-19 vaccination in SARS-CoV-2 naïve residents of nursing homes.
detectable neutralizing Ab to the B.1.351 variant. In contrast, SARS-CoV-2 infected residents had high responses to mRNA vaccination, with Ab levels comparable to infected staff. Cluster analysis revealed that ...
Strategy to Develop and Evaluate a Multiplex RT-ddPCR in Response to SARS-CoV-2 Genomic Evolution.
virus evolution and compromise the accuracy of the diagnostic tests. Therefore, PCR-based SARS-CoV-2 diagnostics should be evaluated and evolve together with the rapidly increasing number of new variants ...
Functional Analysis of Human and Feline Coronavirus Cross-Reactive Antibodies Directed Against the SARS-CoV-2 Fusion Peptide.
Coronavirus Swine Vero Cells Abstract: To face the continuous emergence of SARS-CoV-2 variants, broadly protective therapeutic antibodies are highly needed. We here focused on the fusion peptide (FP) region of ...
NATIONAL SURVEILLANCE OF SARS-COV-2 IN WASTEWATER- Last developments and results- May 2021
hospitalizations, changes in testing policy, etc.) in the light of the emergence of SARS-CoV-2 variants of concern. Although further developments are still ongoing to better define the predictive performance of the ...
Conceptual causal framework to assess the effect of SARS-CoV-2 variants on COVID-19 disease severity among hospitalized patients
allows to study the effect of SARS-CoV-2 variants on COVID-19 disease severity among hospitalized patients. METHODS: A causal model is defined and visualized using a Directed Acyclic Graph (DAG), in which ...
Deepening of In Silico Evaluation of SARS-CoV-2 Detection RT-qPCR Assays in the Context of New Variants
above 99%. Additionally, some mutations specific to new SARS-CoV-2 variants of concern were found to be located in oligonucleotide annealing sites. This might impact the strategy to be considered for ...
Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.
started in December 2019. COVID-19 cases are confirmed by the detection of SARS-CoV-2 RNA in biological samples by RT-qPCR. However, limited numbers of SARS-CoV-2 genomes were available when the first ...
Exploring the added value of Whole Genome Sequencing in routine and pandemic viral surveillance
SARS-CoV-2 and its variants present in wastewater. This will enable trying out this approach on real wastewater samples in the near future. Manuscript versions: File: Version: Published Full text access: ...
A general approach to identify low-frequency variants within influenza samples collected during routine surveillance.
Nancy Roosens; Kevin Vanneste Source: Microb Genom, Volume 8, Issue 9 (2022) Keywords: COVID-19 Genome, Viral Humans Influenza A Virus, H3N2 Subtype Influenza, Human SARS-CoV-2 Abstract: Influenza viruses ...
Optimization and Application of a Multiplex Digital PCR Assay for the Detection of SARS-CoV-2 Variants of Concern in Belgian Influent Wastewater.
of emerging SARS-CoV-2 variants of concern (VOC) in influent wastewater (IWW) samples. Key mutations were targeted in the different VOC strains, including SΔ69 /70 deletion, N501Y, SΔ241 and SΔ157. The ...