Résultats de la recherche - 43 results
The EMA PRIME procedure in an accelerated assessment environment for vaccine licensure: Experiences from quality (CMC) assessors. A case study for Ebola vaccine.
Publication Type: Scientific poster, presentation or proceeding Authors: Wim Van Molle; Koen Brusselmans Source: 2020 PDA EUROPE- Driving Biopharmaceutical Innovations & Sustainability BioManufacturing (2020) Health Topics: Effectiveness and safety o ...
Chemical and toxciological characterization of e-liquid cigarettes
e-liquid refills. First, a comprehensive literature search was performed to obtain an overview about the chemical composition of the e-liquids and the analytical methods used for their detection. Although the ...
Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.
human reference genome and 2624 closely related other respiratory viral genomes. The specificity of the assays was generally good and stable over time. An exception is the first method developed by the ...
Characterization and hazard identification of substandard and falsified antimicrobials encountered in Belgium
half of the samples were underdosed, resulting in a potential lower efficacy and so may aggravate illness of patients and induce bacterial resistance [2]. Moreover, in order to have an in-depth ...
Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market.
these 36 compounds within 18 min (including wash and equilibration step). It was validated for sensitivity, selectivity and matrix effects. Within an analysis time of 32 min, the UHPLC- DAD method could ...
Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market
selectivity and matrix effects. Within an analysis time of 32 min, the UHPLC- DAD method could quantify 32 compounds (4 showed insufficient UV absorbance) and resulted in sufficient selectivity, necessary since ...
A pragmatic bottom-up approach to harmonize the units of clinical chemistry tests among Belgian clinical laboratories, focusing on immunoassays.
Harmonization of units is an important step to improve the comparability of clinical chemistry results, but few examples exist of successful harmonization efforts. We present the results of a pragmatic approach ...
Identification of Flavouring Substances of Genotoxic Concern Present in E-Cigarette Refills
increased significantly. An important contributor to this trend is the availability of a wide variety of flavours used in e-liquid refills. However, the role of these flavouring components in the potential ...
Chemometrical analysis of fingerprints for the detection of counterfeit and falsified medicines
Keywords: aims an analysi analysis AS at Chemometrics Control Counterfeit Counterfeit medicines data detection health Literature Medicine Multivariate ON Practice PRACTICES public public health Public-health ...
Analysis of illegal peptide drugs via HILIC-DAD-MS.
an analytical method based on hydrophilic interaction liquid chromatography (HILIC) to identify and quantify the most frequently encountered illegal peptides on the European market. For this objective, ...