Résultats de la recherche - 43 results
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
onset of intracellular viral RNA synthesis. Drug-resistant mutants carry the E291G mutation in the viral RNA-dependent RNA polymerase (RdRp). AG110-resistant virus is cross-resistant to the cyclic urea ...
Even attenuated bovine leukemia virus proviruses can be pathogenic in sheep.
p.10195-200 (2007) Keywords: Amino Acid Motifs Animals Cattle Cell Transformation, Viral DNA Mutational Analysis Enzootic Bovine Leukosis Leukemia Virus, Bovine Lymphoma Membrane Proteins Sequence Deletion ...
Complete suppression of viral gene expression is associated with the onset and progression of lymphoid malignancy: observations in Bovine Leukemia Virus-infected sheep.
nontransformed counterparts. RESULTS: In the first animal, we observed the emergence of a genetically modified provirus simultaneously with leukemia onset. We found a Tax-mutated (TaxK303) replication-deficient provirus in the ...
Lethality and molecular characterization of an HPAI H5N1 virus isolated from eagles smuggled from Thailand into Europe.
neuraminidase (NA) sequences clustered within the Z genotype and were closely related to strains circulating in Thailand during 2004, although some mutations in the HA were evident, notably a unique arginine (R) ...
Avian influenza: mini-review, European control measures and current situation in Asia.
Animals Asia Birds Communicable Disease Control Disease Outbreaks Europe Humans Influenza A virus Influenza in Birds Mutation Risk Factors Species Specificity Abstract: Avian influenza (AI) is a highly ...
Protection of rabbits against enteropathogenic Escherichia coli (EPEC) using an intimin null mutant.
p.22 (2006) Keywords: Adhesins, Bacterial Animals Bacterial Vaccines Diarrhea Escherichia coli Escherichia coli Infections Escherichia coli Proteins Gene Deletion Mutation Rabbits Abstract: BACKGROUND: ...
Vaccination of chicken embryos with escape mutants of La Sota Newcastle disease virus induces a protective immune response.
M Molecular Sequence Data Mutation Newcastle Disease Newcastle disease virus Sequence Analysis, DNA Specific Pathogen-Free Organisms Vaccines, Attenuated Viral Fusion Proteins Viral Vaccines Abstract: To reduce ...
AggA is required for aggregation and increased biofilm formation of a hyper-aggregating mutant of Shewanella oneidensis MR-1.
Microbiology, Volume 152, Issue Pt 3, p.721-9 (2006) Keywords: Bacterial Adhesion Bacterial Proteins Biofilms Gene Expression Regulation, Bacterial Mutation Oligonucleotide Array Sequence Analysis Proteomics ...
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
Johan Source: J Virol, Volume 80, Issue 1, p.149-60 (2006) Keywords: Antiviral Agents Diarrhea Virus 1, Bovine Viral Drug Resistance, Viral Imidazoles Lethal Dose 50 Mutation Pestivirus Pyridines RNA ...
Point mutations in an infectious bovine viral diarrhoea virus type 2 cDNA transcript that yields an attenuated and protective viral progeny.
(2005) Keywords: Animals Bovine Virus Diarrhea-Mucosal Disease Cattle Diarrhea Viruses, Bovine Viral DNA, Complementary Point Mutation Vaccination Vaccines, Attenuated Viral Vaccines virulence Abstract: An ...