Résultats de la recherche - 114 results

New challenges in perioperative management of pancreatic cancer.

5-year survival rate has remained low and usually does not exceed 5%. Only 20%-25% of patients present with potentially resectable disease and surgery represents the only chance for a cure. After decades ...

Genotoxicity testing of 3,4,5-trimethylfuran-2(5H)-one, a compound from plant-derived smoke with germination inhibitory activity.

Environ Mutagen, Volume 778, p.1-5 (2015) Keywords: 4-Nitroquinoline-1-oxide Benzopyrenes Cell Line, Tumor Cell Survival Furans Genes, Reporter Germination Hepatocytes Humans Luciferases Mutagenicity Tests ...

A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus.

King, Donald P; Neyts, Johan; Kris De Clercq Source: Biochem Biophys Res Commun, Volume 455, Issue 3-4, p.378-81 (2014) Keywords: Animals Antiviral Agents Benzimidazoles Cell Line Cell Survival ...

The effect of smoking on the duration of life with and without disability, Belgium 1997-2011.

(DFLE)) and with disability (Disability Life Expectancy (DLE)) and (2) to estimate the extent to which these effects are due to better survival or reduced disability in never smokers. METHODS: Data on ...

Foodborne cereulide causes beta-cell dysfunction and apoptosis.

study the effects of cereulide, a food toxin often found at low concentrations in take-away meals, on beta-cell survival and function. METHODS: Cell death was quantified by Hoechst/Propidium Iodide in ...

Protective effect of different anti-rabies virus VHH constructs against rabies disease in mice.

directly into the brain or systemically, by intraperitoneal injection, 24 hours after virus challenge. Anti-rabies VHH were able to significantly prolong survival or even completely rescue mice from disease. ...

Anti-mycobacterial activity of 1,3-diaryltriazenes.

Polanc, Slovenko; Huygen, Kris; Košmrlj, Janez Source: Eur J Med Chem, Volume 77, p.193-203 (2014) Keywords: Animals Antitubercular Agents Cell Line Cell Survival Dose-Response Relationship, Drug ...

Sustained stimulation and expansion of Tregs by IL2 control autoimmunity without impairing immune responses to infection, vaccination and cancer.

Factors Vaccination Abstract: Interleukin 2 (IL2) is the key cytokine supporting survival and function of regulatory T cells (Tregs). We recently reported that low-dose IL2 safely expands/stimulates Tregs ...

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK651

Mice,Knockout ON oncology pathology pharmacology physiology protein Protein Kinases regulation Research Research Support response result results Role SB- IM stress survival Target Tissue TOR Serine-Threonine ...

Patterns and trends in human papillomavirus-related diseases in Central and Eastern Europe and Central Asia.

p.H32-45 (2013) Keywords: Asia, Central Europe, Eastern Humans incidence Neoplasms Papillomavirus Infections prevalence Survival Analysis Abstract: This article provides an overview of cervical cancer and ...

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