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Development of a Droplet Digital PCR to Monitor SARS-CoV-2 Omicron Variant BA.2 in Wastewater Samples
RT-ddPCR method that targets the T19I amino acid mutation in the spike protein of the SARS-CoV-2 genomes, which is specific to the BA.2 variant (omicron). The T19I assay was evaluated both in silico and in ...
Development of a Droplet Digital PCR to Monitor SARS-CoV-2 Omicron Variant BA.2 in Wastewater Samples.
genomes, which is specific to the BA.2 variant (omicron). The T19I assay was evaluated both in silico and in vitro for its inclusivity, sensitivity, and specificity. Moreover, wastewater samples were used as ...
Homologous and Heterologous Prime-Boost Vaccination: Impact on Clinical Severity of SARS-CoV-2 Omicron Infection among Hospitalized COVID-19 Patients in Belgium
Lize Cuypers; Belgian Collaborative Group on COVID-19 Hospital Surveillance; COVID-19 Genomics Belgium; Annie Robert; Nina Van Goethem Source: Vaccines, Volume 11, Issue 2 (2023) Abstract: We ...
Development of strain-level shotgun metagenomics approaches to detect and characterize microbiological contaminants in the context of food safety
have always been analyzed and characterized after isolation. Since the advent of second generation sequencing, it has been possible to characterize the complete genome of these isolates to the SNP level. ...
Genomic Insights into Methicillin-Resistant Staphylococcus aureus spa type t899 Isolates Belonging to Different Sequence Types
Publication Type: Peer reviewed scientific article Authors: Tegegne, Henok Ayalew; Ivana Koláčková; Martina Florianová; P Wattiau; Tereza Gelbíčová; Cécile Boland; Jean-Yves Madec; Marisa Haenni; Renata Karpíšková Source: Applied and Environmental Microbi ...
Combined Phylogeographic Analyses and Epidemiologic Contact Tracing to Characterize Atypically Pathogenic Avian Influenza (H3N1) Epidemic, Belgium, 2019.
epidemic that occurred in Belgium during 2019. Virus genomes from 104 clinical samples originating from 85% of affected farms were sequenced. A spatially explicit phylogeographic analysis confirmed ...
Using a combination of short and long read sequencing to investigate the diversity in plasmid- and chromosomally encoded extended-spectrum-beta-lactamases (ESBL) in clinical Shigella and Salmonella isolates in Belgium
Publication Type: Peer reviewed scientific article Authors: Bas Berbers; Kevin Vanneste; Nancy Roosens; Marchal,K.; Pieter-Jan Ceyssens; Sigrid C.J. De Keersmaecker Source: Microbial Genomics ...
Do genomic passports leave us more vulnerable or less vulnerable? Perspectives from an online citizen engagement
genomic passport Abstract: Since genomics is becoming commonplace in healthcare for the diagnosis, treatment, and prevention, the prospect of generating a genomic passport for all citizens is gaining ...
Development of a portable on-site applicable metagenomic data generation workflow for enhanced pathogen and antimicrobial resistance surveillanceAbstract
genomica Transversal activities in applied genomics Manuscript versions: DOI: https://sciensano.be/en/10.1038/s41598-023-46771-z File: Version: Published Full text access: Public Access Full text ...
Comparison of 6 DNA extraction methods for isolation of high yield of high molecular weight DNA suitable for shotgun metagenomics Nanopore sequencing to detect bacteriaAbstractBackgroundResultsConclusion
Publication Type: Peer reviewed scientific article Authors: Mathieu Gand; Bram Bloemen; Kevin Vanneste; Nancy Roosens; Sigrid C.J. De Keersmaecker Source: BMC Genomics, Volume 24, Issue 1 (2023) ...