Search results - 57 results

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Birgit Mertens Source: 57th Congress of the European Societies of Toxicology, Ljubljana, Slovenia (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to testing and assessment ...

Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals

Source: 57th Congress of the European Societies of Toxicology (Eurotox 2023), Ljubljana, Slovenia (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health ...

The SILIFOOD application: a new tool to support risk assessment of non-evaluated food contact materials substances

Manganaro; Els Van Hoeck; Birgit Mertens Source: 57th Congress of the European Societies of Toxicology (Eurotox 2023), Ljubljana, Slovenia (2023) Keywords: Chemical risk assessment food contact materials QSAR ...

A Systematic Review on Pollutant Induced Cardiotoxicity: Providing a Toxicological Foundation for NAM Development and Regulatory Acceptance

Ritskes-Hoitinga; R. Gehring Source: 12th World Congress on Alternatives and Animal Use in the Life Sciences, Nigara falls, Canada (2023) Keywords: Cardiotoxicity pollutants systematic review toxicological evidence ...

In silico methods for chromosome damage

Issue 8, New York (2022) ISBN: 978-1-0716-1960-5 Abstract: Due to the link with serious adverse health effects, genotoxicity is an important toxicological endpoint in each regulatory setting with respect ...

Chemical and toxciological characterization of e-liquid cigarettes

PhD thesis was therefore to first determine the chemical composition of the liquids used in e-cigarettes (e-liquid) and next to investigate toxicological aspects of flavouring substances present in ...

Introduction to toxicology

Publication Type: Scientific poster, presentation or proceeding Authors: Marie-Noelle Blaude Source: Beltox course “Introduction to Toxicology and Ecotoxicology as the Scientific Basis for ...

Regulatory aspects and example of read-across

Publication Type: Scientific poster, presentation or proceeding Authors: Marie-Noelle Blaude Source: Beltox course “Introduction to Toxicology and Ecotoxicology as the Scientific Basis for ...

DETERMINATION OF ALLERGENIC FRAGRANCE INGREDIENTS IN FEMININE ABSORBENT HYGIENE PRODUCTS AND LUBRICANTS

a real-life exposure scenario to gain a better understanding of the leaching of these fragrances. At last, a risk assessment was made using the estimated exposure and the toxicological data available. Method: ...

Study on implications on the requirements for submission of toxicological information, restricitions and administrative consequences of the draft revised guideline on Food Contact Materials

Publication Type: Sci. report, recommendat°, guidance doc., directive, monograph Authors: Els Van Hoeck; Birgit Mertens; Séverine Goscinny; N'Goy,T.; Van paemel,M.; F. Bolle; Christiane Vleminckx Source: EFSA, Parma, Italy, p.117 (2015) Keywords: con ...

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