Clinical Evolution and Disease Burden in Belgian Cystic Fibrosis Patients: effect of Newborn Screening?

Last updated on 2-1-2024 by Géraldine Daneau

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Objectives: We compared the clinical evolution and disease burden of 3 groups of Belgian children with cystic fibrosis (CF) depending on the mode of diagnosis: meconium ileus (MI), newborn screening (NBS) and clinical diagnosis (non-NBS) at 1-, 2- and 6 years of age.Methods: We conducted a retrospective observational cohort study based on data collected from the Belgian CF Registry report of 2016 including patients diagnosed between January 2006 and December 2016. Results: 306 CF patients were enrolled. Age at diagnosis was the lowest in MI patients (median 0.12 months, IQ

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