The Importance of Quality Control of LSDV Live Attenuated Vaccines for Its Safe Application in the Field.

Last updated on 21-12-2021 by Andy Haegeman

Public Access

Published

Peer reviewed scientific article

Anglais

Résumé:

Vaccination is an effective approach to prevent, control and eradicate diseases, including lumpy skin disease (LSD). One of the measures to address farmer hesitation to vaccinate is guaranteeing the quality of vaccine batches. The purpose of this study was to demonstrate the importance of a quality procedure via the evaluation of the LSD vaccine, Lumpivax (Kevevapi). The initial PCR screening revealed the presence of wild type LSD virus (LSDV) and goatpox virus (GTPV), in addition to vaccine LSDV. New phylogenetic PCRs were developed to characterize in detail the genomic content and a vacci…

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