Last updated on 23-8-2019 by Anonymous (non vérifié)
Peer reviewed scientific article
Anglais
SCIENSANO
Mots-clés
Résumé:
INTRODUCTION: The Belgian national External Quality Assessment Scheme performed a survey to assess the effect of the direct oral anticoagulant apixaban on the coagulation assays prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen and antithrombin as performed with a large number of reagent/instrument combinations.
METHODS: Four lyophilized plasma samples spiked with apixaban (0, 41, 94 and 225 ng/mL) were sent to the 195 Belgian and Luxembourg clinical laboratories performing coagulation testing.
RESULTS: PT and aPTT were barely influenced at the concentrat…