SycE, a chaperone-like protein of Yersinia enterocolitica involved in Ohe secretion of YopE.

Last updated on 23-8-2019 by Anonymous (non vérifié)

Peer reviewed scientific article



Pathogenic yersiniae secrete a set of 11 anti-host proteins called Yops. The yop genes, scattered around the pYV plasmid, constitute a thermoinduced regulon controlled by the product of virF gene. The secretion of the Yops also requires the presence of the products of the other vir genes and operons, namely virA, virB and virC. The large virC operon and presumably some genes of the virA region encode a new secretion system. Mutations in any of these vir genes impair the production of all the Yops. In contrast, mutations in the yerA locus, located close to yopE, specifically abolish the expr…

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