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Résultats de la recherche - 9 results
Progressive Control of Streptococcus agalactiae-Induced Innate Inflammatory Response Is Associated with Time Course Expression of MicroRNA-223 by Neutrophils.
Animals Chemokine CXCL1 Chemokine CXCL2 Chemokines Cytokines Inflammation Interleukin-1beta Lung Macrophages Male mice Mice, Inbred C57BL MicroRNAs Monocytes Neutrophils Pneumonia Streptococcus agalactiae ...
Antitumoral activity of parvovirus-mediated IL-2 and MCP-3/CCL7 delivery into human pancreatic cancer: implication of leucocyte recruitment
PDAC cells with the rodent parvovirus H- 1PV. In this study, the therapeutic efficacy of parvovirus-mediated delivery of three distinct cyto/chemokines (Il-2, MCP-3/ CCL7 and IP-10/ CXCL10) was evaluated ...
The role of CXC chemokines in the transition of chronic inflammation to esophageal and gastric cancer
tumor development by stimulating angiogenesis and by favoring metastasis of CXCR4-positive tumor cells to distant organs producing SDF-1/ CXCL12. Furthermore, these angiogenic chemokines also directly ...
The expression and role of CXC chemokines in colorectal cancer
of a tumor-specific immune response by attracting leukocytes, stimulation of tumor cell proliferation and metastasis. Here, we review the expression and complex roles of CXC chemokines (CXCL1 to ...
Isotypic neutralizing antibodies against mouse GCP-2/CXCL6 inhibit melanoma growth and metastasis
302, Issue 1, Number 62, p.54- 62 (2011) Keywords:)Melanoma chemokine Granulocyte chemotactic protein-2 (GCP-2 Abstract: The chemokine granulocyte chemotactic protein (GCP)-2/ CXCL6 promotes tumor growth ...
Expression of angiostatic platelet factor-4var/CXCL4L1 counterbalances angiogenic impulses of vascular endothelial growth factor, interleukin-8/CXCL8, and stromal cell-derived factor 1/CXCL12 in esophageal and colorectal cancer
factor [SDF]-1/ CXCL12 and interleukin [IL]-8/ CXCL8) and angiostatic (platelet factor [PF]-4var/ CXCL4L1 and inducible protein [IP-10]/ CXCL10) chemokines was examined in human colorectal and esophageal ...
CC chemokine ligand-2 synergizes with the nonchemokine G protein-coupled receptor ligand fMLP in monocyte chemotaxis, and it cooperates with the TLR ligand LPS via induction of CXCL8
p.671- 680 (2009) Keywords: chemokine chemotaxis cytokine monocyte neutrophile Abstract: During inflammatory reactions, endogenously produced cytokines and chemokines act in a network and interact with ...
Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4
mechanism to regulate inflammation. In this study, we describe modification of the CXC chemokine stromal cell-derived factor 1alpha/ CXCL12 by peptidylarginine deiminase (PAD) that converts arginine residues ...
Stimulation of angiostatic platelet factor-4 variant (CXCL4L1/PF-4var) versus inhibition of angiogenic granulocyte chemotactic protein-2 (CXCL6/GCP-2) in normal and tumoral mesenchymal cells
through leukocyte attraction and angiogenesis. Here, we demonstrate that CXCL4L1 /platelet factor-4 variant (PF-4var), a highly angiostatic chemokine, is poorly chemotactic for phagocytes and is inducible ...