Résultats de la recherche - 96 results

A Transcriptomic Biomarker to Classify Chemical-Induced Histone Deacetylase Inhibition in Human HepaRGTM Cells

Service:  Évaluation des risques et de l'impact sur la santé Risico- en gezondheidsimpactevaluatie Risk and health impact assessment Full text language:  English Category:  C32 FOS Classification:  3.03 ...

Impact of short-term exposure to air pollution on natural mortality and vulnerable populations: a multi-city case-crossover analysis in Belgium

Publication Type: Peer reviewed scientific article Authors: Claire Demoury; Raf Aerts; Finaba Berete; Lefebvre, Wouter; Pauwels, Arno; Vanpoucke, Charlotte; Johan Van der Heyden; Eva M De Clercq ...

Pollutant exposure and myocardial injury: Protocol and progress report for a toxicological systematic mapping review.

Donzelli, Gabriele; Ritskes-Hoitinga, Merel; Gehring, Ronette Source: ALTEX (2023) Abstract: An increasing body of evidence identifies pollutant exposure as a risk factor for cardiovascular disease (CVD), ...

The GENOMARK transcriptomic biomarker: a new approach methodology for genotoxicity (Qualitative and quantitative aspects)

Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Carole Yauk; Stefaan Verhulst; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens ...

An AOP-based IATA to pave the way toward animal-free genotoxicity testing

Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens Source: Joint 3R Symposium 2023, Brussels, Belgium (2023) Keywords: adverse outcome pathways genotoxicity ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; ...

Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals

Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Matthew Meier; Carole Yauk; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; ...

Reducing the Burden on Animals and the Heart: An Evidence-Based Approach to Cardiotoxicity Assessment

Martin Paparella Source: 12th World Congress on Alternatives and Animal Use in the Life Sciences, Nigara falls, Canada (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to ...

A Systematic Review on Pollutant Induced Cardiotoxicity: Providing a Toxicological Foundation for NAM Development and Regulatory Acceptance

Ritskes-Hoitinga; R. Gehring Source: 12th World Congress on Alternatives and Animal Use in the Life Sciences, Nigara falls, Canada (2023) Keywords: Cardiotoxicity pollutants systematic review toxicological evidence ...

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