Résultats de la recherche - 689 results
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
the knowledge on resistance mutations which is limited for especially 2nd-line and new drugs, (b) do not distinguish living from death cells, (c) ignore all intrinsic resistance mechanisms like efflux ...
Clinical Evaluation of INNO-LiPA HPV Genotyping II Assay Using the VALGENT Framework.
VALGENT is designed to assess the analytical and clinical performance of HPV tests with genotyping capacity. The VALGENT-3 panel comprised 1300 consecutive cervical cell specimens enriched with 300 samples ...
Differences in antigenic sites and other functional regions between genotype A and G mumps virus surface proteins.
B-cell epitopes and in N-linked glycosylation sites on the HN protein. There were eight variable amino acid positions specific to genotype A or genotype G sequences in five known B-cell epitopes of the HN ...
Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.
incomplete understanding of the pathogenesis. MALT1 mediates activation of several immune cell types and is involved in the proliferation and survival of cancer cells. MALT1 acts as a scaffold protein for ...
Multivalent binding of herpesvirus to living cells is tightly regulated during infection.
the cell surface. While multiple parallel interactions would allow strong virus attachment, a low number of bonds could be preferred to allow lateral diffusion toward specific receptors and to promote ...
Preparing cDNA Libraries from Lytic Phage-Infected Cells for Whole Transcriptome Analysis by RNA-Seq.
Publication Type: Peer reviewed scientific article Authors: Blasdel, Bob; Pieter-Jan Ceyssens; Lavigne, Rob Source: Methods Mol Biol, Volume 1681, Issue 1681, Number 1941 (2018) Keywords: Bacteriophage RNA-seq Abstract: Whole genome wide analysis of trans ...
Y-box-binding protein 1 supports the early and late steps of HIV replication.
replication. YB-1 depletion resulted in a 10-fold decrease in HIV-1 replication in different cell lines. Dissection of the replication defects revealed that knockdown of YB-1 is associated with a 2- to 5-fold ...
Subcutaneous Granulomatous Inflammation due to Basidiobolomycosis: Case Reports of 3 Patients in Buruli Ulcer Endemic Areas in Benin.
widely available in endemic areas and with varying sensitivity. A combination of histopathological findings, namely, granulomatous inflammation with giant cells, septate hyphal fragments, and the ...
Allergic Asthma Favors Growth in the Lungs of Infected Mice.
dense aggregates of infected cells composed mainly of alveolar macrophages (CD11 c F4 /80 MHCII) surrounded by neutrophils (Ly-6G). Asthma-induced susceptibility appears to be dependent on CD4 T cells ...
Genome Editing in Agriculture: Methods, Applications, and Governance—A paper in the series on The Need for Agricultural Innovation to Sustainably Feed the World by 2050
(CAST), Volume 60, Issue 60 (2018) Abstract: Genome editing is the process of making precise, targeted sequence changes in the deoxyribonucleic acid of living cells and organisms. Recent advances have made ...