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Relative response factors and multiple regression models in liquid chromatography to quantify low-dosed components using alternative standards-proof of concept: total Δ9-THC content in cannabis flowers using CBD as reference.
classical RRF s often fail in lower concentration ranges. For this purpose, the determination of the total Δ9-tetrahydrocannabinol (Δ9- THC + Δ9- THC-A) content in dried cannabis flowers, using UHPLC- DAD, ...