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The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
Pyrazoles RNA Replicase Structure-Activity Relationship Virus Replication Abstract: Ethyl 2-methylimidazo [1,2-a]pyrrolo [2,3-c]pyridin-8-carboxylate (AG110) was identified as a potent inhibitor of pestivirus ...