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Résultats de la recherche - 31 results
Unraveling clonal CD8 T cell expansion and identification of essential factors in γ-herpesvirus-induced lymphomagenesis.
A10 that encodes a transmembrane signaling protein displaying multiple tyrosine residues, with predicted ITAM and SH3 motifs. Impaired A10 expression did not affect AlHV-1 replication in vitro but ...
Genomic comparison between and and analysis of peptide-based biomarkers for serodiagnosis.
to be potential antigens. As synthetic peptides are less costly and variable than recombinant proteins, an approach was performed to identify linear and discontinuous B-cell epitopes in the selected ...
Characterization of two recombinant HVT-IBD vaccines by VP2 insert detection and cell-mediated immunity after vaccination of specific pathogen-free chickens.
and more effective vaccination approaches, including the use of the recombinant turkey herpesvirus vaccine expressing the immunogenic structural VP2 protein of IBDV (recombinant HVT (rHVT)- IBD). The ...
Us3 and Us9 proteins contribute to the stromal invasion of bovine herpesvirus 1 in the respiratory mucosa.
kinase, induces a dramatic cytoskeletal reorganization and BHV-1 Us9, a tail-anchored membrane protein, is required for axonal transport of viruses in neurons. In this study, we investigated the role of Us3 ...
Scalable chromatography-based purification of virus-like particle carrier for epitope based influenza A vaccine produced in Escherichia coli.
Synthetic Vaccines, Virus-Like Particle Veterinary Medicine Viral Matrix Proteins Abstract: Virus-like particles (VLP s) are promising molecular structures for the design and construction of novel vaccines, ...
Small RNA deep sequencing identifies viral microRNAs during malignant catarrhal fever induced by alcelaphine herpesvirus 1.
contribution in MCF of 28 viralmiRNAs clustered in the non-protein-coding region of the AlHV-1 genome, a recombinant virus was produced. The absence of these 28 miRNAs did not affect viral growth in vitro or MCF ...
The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.
aethiops Enterovirus B, Human HeLa Cells Humans Poliovirus RNA-Dependent RNA Polymerase Viral Proteins Abstract: The genus Enterovirus of the family Picornaviridae contains many important human pathogens ...
The combination of attenuated Newcastle disease (ND) vaccine with rHVT-ND vaccine at 1 day old is more protective against ND virus challenge than when combined with inactivated ND vaccine.
Vaccines, Synthetic Viral Fusion Proteins Viral Vaccines Abstract: The recurrent outbreaks of fatal Newcastle disease (ND) in commercial poultry flocks throughout the world indicate that routine vaccinations ...
Vaccination of mice using the West Nile virus E-protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects mice against a lethal challenge.
lPEI-mannose using different administration routes (intramuscular, intradermal and topical). In parallel a heterologous boost with purified recombinant WNV envelope (E) protein was evaluated. While no ...
Substituted 2,6-bis(benzimidazol-2-yl)pyridines: a novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase.
Drug Resistance, Viral Enzyme Inhibitors Hepacivirus Models, Molecular Mutation Protein Conformation Pyridines RNA Replicase Virus Replication Abstract: 2,6-Bis(benzimidazol-2-yl)pyridine (BBP / CSFA-0) ...