Résultats de la recherche - 30 results
Screening of plant food supplements for fraud concerning the presence of medicinal or regulated plants based on multi-dimensional chromatographic fingerprints
based on mass spectrometry and the combination of both. Finally the mass spectrometric approach was chosen to conduct a small market study comprising 21 samples purchased on the Belgian regular market and ...
Simultaneous quantification of Ibuprofen and Paracetamol in combined tablet formulations by UV–VIS spectrophotometry and chemometric modelling
prior separation, thus simplifying sample preparation and reducing waste generation, time and cost of analysis. The aim of this work was to develop reliable and robust chemometric models coupled with UV ...
Mass Spectrometric Fingerprinting to Detect Fraud and Herbal Adulteration in Plant Food Supplements
be superior. The future market studies would adopt MS modeling as the preferred choice. A proof of concept was carried out on 10 real-life samples obtained from illegal sources. The results indicated ...
Illegal medicines observed in the EU
samples, organises specific ring tests, training sessions, symposia and joint market surveillance studies and provides technical guidance for screening and analysis of suspected illegal medicines. To ...
Substandard and falsified ivermectin tablets obtained for self-medication during the COVID-19 pandemic as a source of potential harm.
SF ivermectin samples, intercepted in large quantities by the Belgian regulatory agencies during the period 2021-2022, were analyzed in our official medicines control laboratory. None of the samples (n ...
Characterisation and Hazard identification of substandard and Falsified Antimicrobial Drugs. The CantiBio project 2016-2020
reports of SF antimicrobials have already demonstrated associated adverse drug effects, prolonged illness, deadly outcomes and microbial resistance. The present study, based on suspected samples seized by ...
The strategic change of the API fingerprint programme: from verification of authenticity of API sources to identifying potential quality issues
analysis to Ph. Eur. Monographs, other types of analysis were performed in order to obtain data, allowing to distinct the different API samples according to their origin or manufacturer. The idea was to ...
Screening the capability of vibrational spectroscopic techniques for simultaneous quantification of vitamins B1, B6, and B12 in a powder blend
solvents or reagents in sample preparation, FTIR, NIR and Raman spectroscopy belong to the group of environmentally friendly techniques, known as “green analytical techniques”. Such characteristics ...
Microbial quality analysis of falsified medicines seized by controling agencies
refers to the amount and type of microorganisms present in a sample and reflects the level of biological contamination and associated potential health risks upon consumption of the product. We initially ...
Multidimensional chromatographic fingerprinting combined with chemometrics for the identification of regulated plants in suspicious plant food supplements
the Belgian Federal Agency for Medicines and Health Products, were classified using the above developed models. 10 out of 12 samples were suggestively found to be positive by binary modelling whereas 11 ...